Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | ANPEP | P15144 | 5/20 | 0.31 |
| ▸ | NPEPPS | P55786 | 5/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29043762 | 1.00 | KDM4E (0.31) | KDM4EPKMANPEPNPEPPSHTR2C | |
| SCHEMBL28521252 | 0.88 | HTR2C (0.31) | KDM4EPKMHTR2CHTR2B | |
| SCHEMBL31192291 | 0.88 | HTR2C (0.31) | KDM4EPKMHTR2CHTR2B | |
| SCHEMBL29835052 | 0.86 | ADORA2A (0.38) | ANPEPNPEPPS | |
| SCHEMBL26981136 | 0.86 | ADORA2A (0.38) | ANPEPNPEPPS | |
| SCHEMBL26090156 | 0.85 | HTR2B (0.35) | KDM4EPKMHTR2CHTR2B | |
| SCHEMBL29413061 | 0.85 | HTR2B (0.35) | KDM4EPKMHTR2CHTR2B | |
| SCHEMBL31228871 | 0.81 | NPEPPS (0.35) | ANPEPNPEPPS | |
| SCHEMBL28417275 | 0.80 | ADORA3 (0.33) | KDM4EPKM | |
| SCHEMBL31439405 | 0.80 | ADORA3 (0.33) | KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115362000-A | Gene therapy for neurodegenerative disorders using polynucleotide silencing and replacement | 帕罗斯生物公司 | 2022-11-18 | — | — | CN | disclosed |
| CN-115044570-A | RNA-guided eradication of human JC virus and other polyomaviruses | 英联邦高等教育系统天普大学 | 2022-09-13 | — | — | CN | disclosed |
| CN-114206849-A | Therapeutic methods for treating non-infectious ocular immunoinflammatory disorders | 斯格本斯眼科研究所有限公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-107406854-B | RNA-guided eradication of human JC virus and other polyomaviruses | 英联邦高等教育系统天普大学 | 2022-03-11 | — | — | CN | disclosed |
| CN-107949424-B | TAT-induced CRISPR/endonuclease-based gene editing | 天普大学-联邦高等教育系统 | 2022-03-01 | — | — | CN | disclosed |