SCHEMBL29413061

SCHEMBL29413061

CSc1nc(NC(=O)[C@@H](N)[C@@H](C)O)c2ncn([C@]3(C(N)=O)O[C@H](CO)[C@@H](O)[C@H]3O)c2n1

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ HTR2B P41595 2/20 0.35
▸ HTR2C P28335 1/20 0.35
▸ ADORA3 P0DMS8 2/20 0.33
▸ ADORA1 P30542 1/20 0.33
▸ ADRA2B P18089 1/20 0.32
▸ HTR2A P28223 1/20 0.32
▸ KDM4E B2RXH2 1/20 0.32
▸ PKM P14618 1/20 0.32
▸ TARS1 P26639 2/20 0.32
▸ P2RY1 P47900 1/20 0.31
▸ P2RY12 Q9H244 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26090156 1.00 HTR2B (0.35) HTR2BHTR2CADORA3ADORA1ADRA2B
SCHEMBL16987222 0.86 TARS1 (0.38) ADORA1TARS1
SCHEMBL29435121 0.86 TARS1 (0.38) ADORA1TARS1
SCHEMBL28564130 0.86 TARS1 (0.38) ADORA1TARS1
SCHEMBL29238711 0.86 HTR2B (0.34) HTR2BHTR2CADORA3ADRA2BHTR2A
SCHEMBL29043762 0.85 KDM4E (0.31) HTR2BHTR2CKDM4EPKM
SCHEMBL29407144 0.85 KDM4E (0.31) HTR2BHTR2CKDM4EPKM
SCHEMBL31192291 0.81 HTR2C (0.31) HTR2BHTR2CKDM4EPKM
SCHEMBL28521252 0.81 HTR2C (0.31) HTR2BHTR2CKDM4EPKM
SCHEMBL28894185 0.79 ADORA3 (0.54) ADORA3ADORA1KDM4EPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 249 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4705481-A2 CIRCULAR RNA COMPOSITIONS AND METHODS Orna Therapeutics, Inc. (US) 2026-03-11 — — EP claimed
WO-2025151711-A1 NUCLEIC ACID VACCINES TARGETING METHANOGENS Arkea Bio Corp. (US) 2025-07-17 — — WO claimed
EP-4554616-A1 COMPOSITIONS AND METHODS FOR REDUCING METHANE EMISSIONS IN RUMINANT POPULATIONS Arkea Bio Corp. (US) 2025-05-21 — — EP claimed
WO-2024233308-A2 CIRCULAR RNA COMPOSITIONS AND METHODS ORNA THERAPEUTICS, INC. (US) 2024-11-14 — — WO claimed
EP-4437125-A1 RNA AND DNA ANALYSIS USING ENGINEERED SURFACES Alida Biosciences, Inc. (US) 2024-10-02 — — EP claimed
WO-2024123812-A1 FUSION PROTEINS FOR THE TREATMENT OF CARDIOMETABOLIC DISEASES SHATTUCK LABS, INC. (US) 2024-06-13 — — WO claimed
WO-2024097875-A1 FUSION PROTEINS FOR THE TREATMENT OF NONALCOHOLIC STEATOHEPATITIS SHATTUCK LABS, INC. (US) 2024-05-10 — — WO claimed
WO-2024015366-A1 COMPOSITIONS AND METHODS FOR REDUCING METHANE EMISSIONS IN RUMINANT POPULATIONS Arkea Bio Corp. (US) 2024-01-18 — — WO claimed
WO-2023178182-A1 COMPOSITIONS AND METHODS FOR DETECTION AND TREATMENT OF CORONAVIRUS INFECTION 10X GENOMICS, INC. (US) 2023-09-21 — — WO claimed
EP-4244389-A1 METHOD Ulifetec SAS (FR) 2023-09-20 — — EP claimed
WO-2023097295-A1 RNA AND DNA ANALYSIS USING ENGINEERED SURFACES ALIDA BIOSCIENCES, INC. (US) 2023-06-01 — — WO claimed
WO-2022101440-A1 METHOD ULIFETEC SAS (FR) 2022-05-19 — — WO claimed
WO-2026107055-A1 HEPATITIS B VIRUS VACCINE AND METHODS OF USE THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2026-05-21 — — WO disclosed
CN-122070366-A Cyclic RNA compositions and methods 欧纳医疗公司 2026-05-19 — — CN disclosed
CN-122029278-A Constructs, methods and uses for the preparation of circular RNAs 上海环码生物医药有限公司 2026-05-12 — — CN disclosed
EP-4735033-A2 MRNA-ENCODED TAT WITH ATTENUATED CYTOTOXICITY FOR HIV AND SIV LATENCY REVERSAL The Trustees of the University of Pennsylvania (US) 2026-05-06 — — EP disclosed
WO-2022081694-A1 IN VIVO TARGETING OF FIBROSIS BY ANTI-CD5-TARGETED FAP-CAR T MRNA-LNP THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2022-04-21 — — WO disclosed
WO-2022043551-A2 MULTIVALENT NUCLEIC ACID BASED CORONAVIRUS VACCINES CUREVAC AG (DE) 2022-03-03 — — WO disclosed
WO-2022023559-A1 NUCLEIC ACID ENCODED ANTIBODY MIXTURES CUREVAC AG (DE) 2022-02-03 — — WO disclosed
WO-2022020785-A2 GENE EDITING TO IMPROVE JOINT FUNCTION ORTHOBIO THERAPEUTICS, INC. (US) 2022-01-27 — — WO disclosed
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