Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19555318 | 0.79 | ESR1 (0.41) | ALDH1A1KMT2AKDM4EMEN1SMN1; SMN2 | |
| SCHEMBL22581561 | 0.79 | ADORA2A (0.47) | KMT2ASMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL18041383 | 0.79 | FTO (0.42) | ALDH1A1KMT2AKDM4EMEN1SMN1; SMN2 | |
| SCHEMBL30419628 | 0.77 | L3MBTL1 (0.43) | KDM4ESMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL6369210 | 0.77 | L3MBTL1 (0.43) | KDM4ESMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL2099046 | 0.77 | KDM4E (0.47) | ALDH1A1KMT2AKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL15173772 | 0.77 | ADORA2A (0.44) | KMT2ASMN1; SMN2P4HTMNPC1RAB9A | |
| SCHEMBL691856 | 0.75 | NPC1 (0.43) | ALDH1A1KMT2AKDM4EMEN1SMN1; SMN2 | |
| SCHEMBL2843471 | 0.75 | LMNA (0.54) | SMN1; SMN2NPC1RAB9APOLBLMNA | |
| SCHEMBL1935484 | 0.74 | EPHX2 (0.55) | ALDH1A1KMT2AMEN1SMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023067353-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | ARTIOS PHARMA LIMITED (GB) | 2023-04-27 | — | — | WO | disclosed |