Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24034683 | 1.00 | MCHR1 (0.30) | MCHR1SIGMAR1 | |
| SCHEMBL24034879 | 1.00 | MCHR1 (0.30) | MCHR1SIGMAR1 | |
| SCHEMBL24034785 | 0.86 | SIGMAR1 (0.34) | MCHR1SIGMAR1 | |
| SCHEMBL24034803 | 0.86 | MCHR1 (0.30) | MCHR1SIGMAR1 | |
| SCHEMBL26099482 | 0.86 | MCHR1 (0.30) | MCHR1SIGMAR1 | |
| SCHEMBL24034693 | 0.84 | MCHR1 (0.33) | MCHR1SIGMAR1 | |
| SCHEMBL24034757 | 0.84 | MCHR1 (0.33) | MCHR1SIGMAR1 | |
| SCHEMBL24034842 | 0.81 | MCHR1 (0.33) | MCHR1SIGMAR1 | |
| SCHEMBL26098150 | 0.80 | MCHR1 (0.33) | MCHR1SIGMAR1 | |
| SCHEMBL24034795 | 0.80 | KMT2A (0.34) | MCHR1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230135093-A1 | TRIAZOLYL DERIVATIVES AS GABA A ALPHA5 PAM | HOFFMANN-LA ROCHE INC. (US) | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230135093-A1 | TRIAZOLYL DERIVATIVES AS GABA A ALPHA5 PAM | GABRA5, GABRA3, GABRB3 | MCHR1 452/4885SIGMAR1 145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.