SCHEMBL26099362

SCHEMBL26099362

CS(=O)(=O)N1CC(c2ccccc2)CC1CSc1ccc(C(=O)O)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.36
CA2 P00918 3/20 0.36
CA9 Q16790 3/20 0.36
CA4 P22748 2/20 0.36
GRIN2B Q13224 1/20 0.36
ALDH1A1 P00352 2/20 0.35
POLB P06746 1/20 0.35
THRB P10828 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
USP5 P45974 3/20 0.35
PTGS2 P35354 1/20 0.35
TAS2R14 Q9NYV8 2/20 0.34
KDM1A O60341 2/20 0.34
MCL1 Q07820 1/20 0.33
BCL2A1 Q16548 1/20 0.33
LTA4H P09960 1/20 0.33
AGTR2 P50052 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23932337 0.74 GRIN2B (0.41) CA1CA2CA9GRIN2BALDH1A1
SCHEMBL23932341 0.64 GRIN2B (0.48) GRIN2BALDH1A1SMN1; SMN2KDM1AMEN1
SCHEMBL14569706 0.62 EPHX2 (0.40) ALDH1A1SMN1; SMN2MEN1KMT2AHPGD
SCHEMBL20005783 0.62 NPSR1 (0.54) ALDH1A1POLBSMN1; SMN2USP5KMT2A
SCHEMBL4406866 0.61 PKM (0.43) CA1CA2CA9ALDH1A1SMN1; SMN2
SCHEMBL7225805 0.61 NPY5R (0.49) CA1CA2CA9USP5HDAC6
SCHEMBL25362834 0.61 AKR1C3 (0.41) GRIN2BALDH1A1POLBSMN1; SMN2MEN1
SCHEMBL5576810 0.61 AKR1C3 (0.41) GRIN2BALDH1A1POLBSMN1; SMN2MEN1
SCHEMBL25362718 0.61 AKR1C3 (0.41) GRIN2BALDH1A1POLBSMN1; SMN2MEN1
SCHEMBL24015598 0.61 RIPK1 (0.50) ALDH1A1KDM1AMEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4422618-A1 LOX ENZYME INHIBITING METHODS AND COMPOSITIONS Anovia Biosciences, Inc. (US) 2024-09-04 EP disclosed
US-12016864-B2 LOX enzyme inhibiting methods and compositions ANOVIA BIOSCIENCES, INC. (US) 2024-06-25 US disclosed
US-20230390299-A1 LOX ENZYME INHIBITING METHODS AND COMPOSITIONS ANOVIA BIOSCIENCES INC (US) 2023-12-07 US disclosed
WO-2023076567-A1 LOX ENZYME INHIBITING METHODS AND COMPOSITIONS ANOVIA BIOSCIENCES, INC. (US) 2023-05-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230390299-A1 LOX ENZYME INHIBITING METHODS AND COMPOSITIONS LOX, LOXL1, LOXL2 CA1 2072/4885CA2 1442/4885CA9 1022/4885
US-12016864-B2 LOX enzyme inhibiting methods and compositions LOX, LOXL1, LOXL2 CA1 580/4885CA2 274/4885CA9 270/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.