Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.46 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | USP7 | Q93009 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26100377 | 0.94 | LMNA (0.55) | LMNAGAAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL26097193 | 0.93 | MAPT (0.57) | LMNAGAAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL26098861 | 0.91 | MAPT (0.51) | LMNAGAAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL26097738 | 0.90 | MAPT (0.54) | LMNAGAAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL26098494 | 0.88 | MAPT (0.56) | LMNAGAAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL26099407 | 0.88 | MAPT (0.50) | LMNAGAAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL26099622 | 0.87 | MAPT (0.56) | LMNAGAAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL31666079 | 0.86 | ALDH1A1 (0.48) | LMNAGAAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL26098464 | 0.86 | ALDH1A1 (0.48) | LMNAGAAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL26454732 | 0.86 | MAPT (0.68) | LMNAGAAMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12370183-B2 | Compositions and methods for treating malaria | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2025-07-29 | — | — | US | disclosed |
| US-20230139910-A1 | COMPOSITIONS AND METHODS FOR TREATING MALARIA | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2023-05-04 | — | — | US | disclosed |
| US-20230139910-A1 | COMPOSITIONS AND METHODS FOR TREATING MALARIA | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2023-05-04 | — | — | US | disclosed |
| US-20230139910-A1 | COMPOSITIONS AND METHODS FOR TREATING MALARIA | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12370183-B2 | Compositions and methods for treating malaria | G6PD, QDPR, FASN | LMNA 969/4885GAA 269/4885MAPT 1034/4885 |
| US-20230139910-A1 | COMPOSITIONS AND METHODS FOR TREATING MALARIA | G6PD, QDPR, FASN | LMNA 969/4885GAA 269/4885MAPT 1034/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.