Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | DGKA | P23743 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18470077 | 1.00 | TSHR (0.39) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL13313904 | 0.95 | TSHR (0.39) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL26428512 | 0.91 | MEN1 (0.46) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL3698562 | 0.91 | MEN1 (0.46) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL16865885 | 0.91 | DGKA (0.41) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL18470076 | 0.91 | ALDH1A1 (0.54) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL7692982 | 0.91 | MEN1 (0.46) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL9888985 | 0.89 | ALDH1A1 (0.56) | TSHRALDH1A1HSD17B10CA2DGKA | |
| SCHEMBL16638373 | 0.88 | CYP4F2 (0.37) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL9936704 | 0.87 | TSHR (0.43) | TSHRALDH1A1CA2DGKAADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163865-B2 | Biocompatible amino acid anhydride polymers | UNIVERSITY OF WASHINGTON (US) | 2012-04-24 | — | — | US | disclosed |
| US-20100015205-A1 | BIOCOMPATIBLE AMINO ACID ANHYDRIDE POLYMERS | WASHINGTON, UNIVERSITY OF (US) | 2010-01-21 | — | — | US | disclosed |
| US-7214757-B2 | Polyurethane elastomers and shaped articles prepared therefrom | EASTMAN KODAK COMPANY (US) | 2007-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100015205-A1 | BIOCOMPATIBLE AMINO ACID ANHYDRIDE POLYMERS | CRYAA, FIBP, LNPEP | TSHR 3125/4885ALDH1A1 1847/4885TP53 1210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.