Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 2/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.42 |
| ▸ | SMO | Q99835 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 3/20 | 0.40 |
| ▸ | FASN | P49327 | 4/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 6/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30429790 | 1.00 | NR1I2 (0.42) | NR1I2CACNA1BSMOPDK1PDK2 | |
| SCHEMBL30430028 | 0.85 | MBTD1 (0.42) | NR1I2CACNA1BSMOPOLBKDM1A | |
| SCHEMBL26100540 | 0.85 | MBTD1 (0.42) | NR1I2CACNA1BSMOPOLBKDM1A | |
| SCHEMBL30430006 | 0.78 | NR1I2 (0.39) | NR1I2CACNA1BSMOKDM1AFASN | |
| SCHEMBL26104208 | 0.76 | SLC6A9 (0.41) | PDK1PDK2PDK3PDK4FASN | |
| SCHEMBL30430083 | 0.76 | SLC6A9 (0.41) | PDK1PDK2PDK3PDK4FASN | |
| SCHEMBL26102005 | 0.76 | NR1I2 (0.41) | NR1I2CACNA1BSMOKDM1AFASN | |
| SCHEMBL30430098 | 0.75 | HSD11B1 (0.59) | SMOPOLBHCRTR1HCRTR2 | |
| SCHEMBL26103330 | 0.72 | RORC (0.47) | POLBKDM1AFASNGPR119 | |
| SCHEMBL30396527 | 0.71 | SCD (0.44) | NR1I2CACNA1BSMOFASNSLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023076219-A2 | ANTAGONISTS OF GPR39 PROTEIN | VASOCARDEA, INC. (US) | 2023-05-04 | — | — | WO | disclosed |
| WO-2023076219-A2 | ANTAGONISTS OF GPR39 PROTEIN | VASOCARDEA, INC. (US) | 2023-05-04 | — | — | WO | disclosed |