Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.42 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | SMO | Q99835 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | FASN | P49327 | 4/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | RBP4 | P02753 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 4/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30430028 | 1.00 | MBTD1 (0.42) | MBTD1L3MBTL3L3MBTL1NR1I2CACNA1B | |
| SCHEMBL30429790 | 0.85 | NR1I2 (0.42) | NR1I2CACNA1BKDM1ASMOHCRTR1 | |
| SCHEMBL26099356 | 0.85 | NR1I2 (0.42) | NR1I2CACNA1BKDM1ASMOHCRTR1 | |
| SCHEMBL26103330 | 0.85 | RORC (0.47) | MBTD1L3MBTL3L3MBTL1KDM1APOLB | |
| SCHEMBL30430483 | 0.85 | L3MBTL3 (0.44) | MBTD1L3MBTL3L3MBTL1NR1I2CACNA1B | |
| SCHEMBL26104742 | 0.85 | L3MBTL3 (0.44) | MBTD1L3MBTL3L3MBTL1NR1I2CACNA1B | |
| SCHEMBL26100203 | 0.82 | KDM1A (0.43) | MBTD1L3MBTL3L3MBTL1KDM1AHCRTR1 | |
| SCHEMBL26103351 | 0.81 | L3MBTL3 (0.47) | MBTD1L3MBTL3L3MBTL1KDM1APOLB | |
| SCHEMBL26101079 | 0.80 | F11 (0.45) | MBTD1L3MBTL3L3MBTL1NR1I2CACNA1B | |
| SCHEMBL30430006 | 0.77 | NR1I2 (0.39) | NR1I2CACNA1BKDM1ASMOHCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4423090-A2 | ANTAGONISTS OF GPR39 PROTEIN | Vasocardea, Inc. (US) | 2024-09-04 | — | — | EP | disclosed |
| WO-2023076219-A2 | ANTAGONISTS OF GPR39 PROTEIN | VASOCARDEA, INC. (US) | 2023-05-04 | — | — | WO | disclosed |
| WO-2023076219-A2 | ANTAGONISTS OF GPR39 PROTEIN | VASOCARDEA, INC. (US) | 2023-05-04 | — | — | WO | disclosed |