Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 3/20 | 0.35 |
| ▸ | LIPE | Q05469 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | P2RY1 | P47900 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | FPR1 | P21462 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26107789 | 0.86 | SCN9A (0.35) | LIPESCN9AALOX5APFEN1 | |
| SCHEMBL26107318 | 0.85 | SCN9A (0.37) | CHRM4LIPESCN9ATRPV1TRPC6 | |
| SCHEMBL26105935 | 0.85 | HTR1A (0.41) | — | |
| SCHEMBL26106392 | 0.81 | SCN9A (0.36) | LIPESCN9AFPR1FPR2 | |
| SCHEMBL26106644 | 0.80 | LIPE (0.42) | CHRM4LIPESCN9ATRPV1TRPC6 | |
| SCHEMBL31474518 | 0.78 | SLC6A2 (0.47) | SCN9A | |
| SCHEMBL30591858 | 0.78 | SCN9A (0.41) | CHRM4LIPESCN9ATRPV1FPR1 | |
| SCHEMBL26108335 | 0.77 | FAAH (0.43) | TRPV1 | |
| SCHEMBL26112177 | 0.77 | PDE10A (0.37) | LIPESCN9AFPR1FPR2ALOX5AP | |
| SCHEMBL26107010 | 0.76 | FAAH (0.44) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183768-A2 | SMALL MOLECULE INHIBITORS OF TEA DOMAIN FAMILY MEMBERS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-09-28 | — | — | WO | disclosed |