Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | NCF1 | P14598 | 5/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 6/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | KRAS | P01116 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29124131 | 0.71 | NCF1 (0.50) | HTR3ANCF1HRH4TSHRMAPK1 | |
| SCHEMBL177816 | 0.71 | HTR3A (0.61) | HTR3ANCF1HRH4LMNAGBA1 | |
| SCHEMBL4770137 | 0.70 | SMN1; SMN2 (0.51) | HRH4TSHRLMNAKMT2AHRH3 | |
| SCHEMBL4262506 | 0.70 | NCF1 (0.56) | NCF1TSHRMAPK1HSD17B10LMNA | |
| SCHEMBL11275047 | 0.68 | NCF1 (0.58) | NCF1TSHRMAPK1HSD17B10LMNA | |
| SCHEMBL12215244 | 0.68 | HTR2C (0.59) | HTR3ANCF1HRH4TSHRHSD17B10 | |
| SCHEMBL25409018 | 0.64 | EGFR (0.34) | HTR3A | |
| SCHEMBL11283343 | 0.64 | NCF1 (0.50) | NCF1TSHRMAPK1HSD17B10LMNA | |
| SCHEMBL11282819 | 0.64 | ALDH1A1 (0.53) | HTR3ATSHRMAPK1HSD17B10LMNA | |
| SCHEMBL30744790 | 0.63 | KDM4E (0.41) | MAPK1HSD17B10KMT2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023071998-A1 | NOVEL PYRIDO OR TRIAZINE-SUBSTITUTED PYRIDO HETEROCYCLIC COMPOUND | 杭州德睿智药科技有限公司 | 2023-05-04 | — | — | WO | disclosed |