Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 1/20 | 0.56 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.56 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.56 |
| ▸ | ASF1A | Q9Y294 | 1/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.50 |
| ▸ | TGM2 | P21980 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | RNF4 | P78317 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11222905 | 0.82 | MAOB (0.59) | ALDH1A1NPC1RAB9A | |
| SCHEMBL6856729 | 0.82 | SRC (0.56) | GFERALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL26508765 | 0.81 | HPGD (0.49) | LPAR1LPAR2LPAR3ASF1AMTNR1B | |
| SCHEMBL30108111 | 0.81 | HPGD (0.49) | LPAR1LPAR2LPAR3ASF1AMTNR1B | |
| SCHEMBL29484309 | 0.81 | MAOB (0.61) | ALDH1A1NPC1RAB9A | |
| SCHEMBL4653369 | 0.81 | HPGD (0.70) | TGM2PGRHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL11482497 | 0.81 | MAOB (0.61) | ALDH1A1NPC1RAB9A | |
| SCHEMBL98478 | 0.81 | MAOB (0.61) | ALDH1A1NPC1RAB9A | |
| SCHEMBL4100666 | 0.80 | TRIM24 (0.59) | ALDH1A1 | |
| SCHEMBL6853633 | 0.79 | SRC (0.53) | GFERALDH1A1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4314005-A1 | GLUCOCORTICOID RECEPTOR AGONISTS | Eli Lilly and Company (US) | 2024-02-07 | — | — | EP | disclosed |
| US-20240018182-A1 | GLUCOCORTICOID RECEPTOR AGONISTS | ELI LILLY AND COMPANY | 2024-01-18 | — | — | US | disclosed |
| US-11787834-B2 | Glucocorticoid receptor agonists | ELI LILLY AND COMPANY (US) | 2023-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240018182-A1 | GLUCOCORTICOID RECEPTOR AGONISTS | NR3C1, NR3C2, MC2R | LPAR1 165/4885LPAR2 237/4885LPAR3 45/4885 |
| US-11787834-B2 | Glucocorticoid receptor agonists | NR3C1, NR3C2, MC2R | LPAR1 165/4885LPAR2 237/4885LPAR3 45/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.