SCHEMBL261122

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL260685	0.80	CYP1A2 (0.43)	ALDH1A1MAPTGAAMEN1KMT2A
	SCHEMBL14876425	0.75	ALDH1A1 (0.47)	ALDH1A1MAPTRAB9AGAAMEN1
	SCHEMBL29923859	0.73	MEN1 (0.58)	ALDH1A1MAPTRAB9APDGFRBFGFR1
	SCHEMBL908565	0.73	MEN1 (0.58)	ALDH1A1MAPTRAB9APDGFRBFGFR1
	SCHEMBL14875760	0.73	ALDH1A1 (0.52)	ALDH1A1MAPTRAB9AGAAMEN1
	SCHEMBL6543923	0.72	PDGFRB (0.50)	ALDH1A1MAPTRAB9APDGFRBFGFR1
	SCHEMBL10087451	0.72	PDGFRB (0.50)	ALDH1A1MAPTRAB9APDGFRBFGFR1
	SCHEMBL10267923	0.72	GPR35 (0.53)	ALDH1A1MAPTRAB9APDGFRBFGFR1
	SCHEMBL27691843	0.72	DNA2 (0.51)	ALDH1A1MAPTRAB9APDGFRBFGFR1
	SCHEMBL5741830	0.72	KMT2A (0.42)	ALDH1A1MAPTMEN1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.