Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | CNR2 | P34972 | 3/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | CSF1R | P07333 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | GSK3A | P49840 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.47 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.47 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30571537 | 1.00 | SLC6A3 (0.56) | SLC6A3SLC6A4SLC6A2CNR2ROCK2 | |
| SCHEMBL19940155 | 0.84 | SLC6A3 (0.55) | SLC6A3SLC6A4SLC6A2CNR2ROCK2 | |
| SCHEMBL30285097 | 0.81 | SLC6A3 (0.63) | SLC6A3SLC6A4SLC6A2CNR2ROCK2 | |
| SCHEMBL7419776 | 0.81 | CNR2 (0.46) | SLC6A3SLC6A4SLC6A2CNR2TSHR | |
| SCHEMBL7248274 | 0.81 | TSHR (0.55) | CNR2TSHRLMNAALDH1A1TDP1 | |
| SCHEMBL8249355 | 0.80 | BCAT2 (0.54) | SLC6A3SLC6A4SLC6A2ROCK2CSF1R | |
| SCHEMBL68818 | 0.79 | SLC6A3 (0.73) | SLC6A3SLC6A4SLC6A2ROCK2CSF1R | |
| SCHEMBL249 | 0.79 | SLC6A3 (0.73) | SLC6A3SLC6A4SLC6A2ROCK2CSF1R | |
| SCHEMBL20936927 | 0.78 | SLC6A3 (0.49) | SLC6A3SLC6A4SLC6A2CNR2ROCK2 | |
| SCHEMBL30285287 | 0.77 | SLC6A3 (0.71) | SLC6A3SLC6A4SLC6A2ROCK2CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183405-A2 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2023-09-28 | — | — | WO | disclosed |