SCHEMBL26121663

SCHEMBL26121663

CC(C)(C)OC(=O)N1CCC(C2CCCNC2)CC1

nearest known ligand 0.51

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 13/20 0.51
HPGD P15428 1/20 0.50
EPHX1 P07099 1/20 0.48
RECQL P46063 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31561507 1.00 GPR119 (0.51) GPR119HPGDEPHX1RECQL
SCHEMBL14497251 0.92 HPGD (0.45) GPR119HPGDEPHX1RECQL
SCHEMBL26100517 0.91 GPR119 (0.53) GPR119HPGDEPHX1RECQL
SCHEMBL26099289 0.91 GPR119 (0.53) GPR119HPGDEPHX1RECQL
SCHEMBL26098762 0.91 GPR119 (0.53) GPR119HPGDEPHX1RECQL
SCHEMBL2881367 0.88 GPR119 (0.55) GPR119HPGDEPHX1RECQL
SCHEMBL2881371 0.88 GPR119 (0.55) GPR119HPGDEPHX1RECQL
SCHEMBL3784890 0.88 GPR119 (0.55) GPR119HPGDEPHX1RECQL
SCHEMBL29026719 0.87 NR1H2 (0.49) GPR119HPGDEPHX1RECQL
SCHEMBL21193938 0.87 NR1H2 (0.49) GPR119HPGDEPHX1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260092050-A1 CHEMOKINE RECEPTOR MODULATORS AND USES THEREOF RAPT THERAPEUTICS INC (US) 2026-04-02 US disclosed
US-20250122208-A1 CHEMOKINE RECEPTOR MODULATORS AND USES THEREOF RAPT THERAPEUTICS, INC. 2025-04-17 US disclosed
CN-119585256-A Chemokine receptor modulators and uses thereof 拉普特医疗公司 2025-03-07 CN disclosed
US-12240837-B2 Chemokine receptor modulators and uses thereof RAPT THERAPEUTICS, INC. (US) 2025-03-04 US disclosed
EP-4504338-A1 CHEMOKINE RECEPTOR MODULATORS AND USES THEREOF RAPT Therapeutics, Inc. (US) 2025-02-12 EP disclosed
US-20230322741-A1 CHEMOKINE RECEPTOR MODULATORS AND USES THEREOF RAPT THERAPEUTICS, INC. 2023-10-12 US disclosed
US-20230322741-A1 CHEMOKINE RECEPTOR MODULATORS AND USES THEREOF RAPT THERAPEUTICS, INC. 2023-10-12 US disclosed
WO-2023196432-A1 CHEMOKINE RECEPTOR MODULATORS AND USES THEREOF RAPT THERAPEUTICS, INC. (US) 2023-10-12 WO disclosed
WO-2023196432-A1 CHEMOKINE RECEPTOR MODULATORS AND USES THEREOF RAPT THERAPEUTICS, INC. (US) 2023-10-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230322741-A1 CHEMOKINE RECEPTOR MODULATORS AND USES THEREOF ACKR3, CCR5, CXCR3 GPR119 177/4885HPGD 437/4885EPHX1 440/4885
US-20260092050-A1 CHEMOKINE RECEPTOR MODULATORS AND USES THEREOF CCR1, CXCR2, CCR2 GPR119 325/4885HPGD 3432/4885EPHX1 2027/4885
US-12240837-B2 Chemokine receptor modulators and uses thereof ACKR3, CCR5, CXCR3 GPR119 177/4885HPGD 437/4885EPHX1 440/4885
US-20250122208-A1 CHEMOKINE RECEPTOR MODULATORS AND USES THEREOF ACKR3, CCR5, CXCR3 GPR119 272/4885HPGD 477/4885EPHX1 400/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.