Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | HBB | P68871 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | TK1 | P04183 | 4/20 | 0.39 |
| ▸ | NT5E | P21589 | 1/20 | 0.38 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.38 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30590024 | 0.90 | LMNA (0.54) | LMNASMN1; SMN2MAPTESR1TSHR | |
| SCHEMBL25400307 | 0.90 | LMNA (0.54) | LMNASMN1; SMN2MAPTESR1TSHR | |
| SCHEMBL31653078 | 0.87 | TK1 (0.52) | TK1 | |
| SCHEMBL31652824 | 0.87 | PYGM (0.44) | LMNASMN1; SMN2TSHRPMP22ALOX12 | |
| SCHEMBL31652926 | 0.87 | TK1 (0.52) | LMNASMN1; SMN2TSHRPMP22ALOX12 | |
| SCHEMBL26270575 | 0.85 | LMNA (0.57) | LMNASMN1; SMN2TSHRPMP22ALOX12 | |
| SCHEMBL31652912 | 0.84 | LMNA (0.39) | LMNASMN1; SMN2ALOX12ADRA1ATK1 | |
| SCHEMBL31652695 | 0.84 | TK1 (0.39) | LMNASMN1; SMN2ALOX12ADRA1ATK1 | |
| SCHEMBL26267954 | 0.83 | LMNA (0.54) | LMNASMN1; SMN2MAPTESR1TSHR | |
| SCHEMBL21345749 | 0.83 | LMNA (0.57) | LMNASMN1; SMN2MAPTESR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250215039-A1 | NUCLEOSIDES FOR TREATING CANCER | PRIMEFOUR THERAPEUTICS INC (US) | 2025-07-03 | — | — | US | disclosed |
| WO-2023192499-A1 | NUCLEOSIDES FOR TREATING CANCER | PRIMEFOUR THERAPEUTICS, INC. (US) | 2023-10-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250215039-A1 | NUCLEOSIDES FOR TREATING CANCER | UNG, OGG1, NTPCR | LMNA 1053/4885SMN1; SMN2 1261/4885MAPT 4543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.