Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 2/20 | 0.36 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.33 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2733461 | 0.87 | KLKB1 (0.36) | KLKB1PARP1PARP2PARP3 | |
| SCHEMBL26133925 | 0.85 | L3MBTL1 (0.40) | KLKB1PARP1PARP2PARP3 | |
| SCHEMBL26135903 | 0.80 | ADORA3 (0.36) | KLKB1PARP1PARP2PARP3 | |
| SCHEMBL26135704 | 0.80 | ADORA3 (0.36) | KLKB1PARP1PARP2PARP3 | |
| SCHEMBL345169 | 0.79 | ADORA2A (0.37) | KLKB1PARP1PARP2PARP3 | |
| Hydrochloric Acid SCHEMBL31096988 | 0.78 | ADORA2A (0.36) | KLKB1PARP1PARP2PARP3 | |
| Thiourea SCHEMBL28847920 | 0.75 | GAA (0.36) | KLKB1PARP1PARP2PARP3 | |
| SCHEMBL28214209 | 0.74 | ADRA1D (0.48) | KLKB1PARP1PARP2 | |
| SCHEMBL28859320 | 0.73 | PARP1 (0.44) | PARP1 | |
| SCHEMBL29002480 | 0.72 | NNMT (0.35) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4499632-A1 | QUINOLINE DERIVATIVES AS MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X2 AND RELATED PRODUCTS | ESCIENT PHARMACEUTICALS, INC. (US) | 2025-02-05 | — | — | EP | disclosed |
| CN-119095839-A | Quinoline derivatives as modulators and related products of Mas-associated G protein receptor X2 | 伊赛恩特制药公司 | 2024-12-06 | — | — | CN | disclosed |
| WO-2023192901-A1 | QUINOLINE DERIVATIVES AS MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X2 AND RELATED PRODUCTS | ESCIENT PHARMACEUTICALS, INC. (US) | 2023-10-05 | — | — | WO | disclosed |