Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26134618 | 0.84 | TP53 (0.41) | SIRT2SIRT1GPR119TP53 | |
| SCHEMBL22536521 | 0.84 | CACNA1G (0.49) | ALDH1A1MAPTLMNAHPGDNPC1 | |
| SCHEMBL29277630 | 0.84 | CACNA1G (0.49) | ALDH1A1MAPTLMNAHPGDNPC1 | |
| SCHEMBL26134495 | 0.83 | ALDH1A1 (0.47) | TDP1ALDH1A1MAPTLMNASIRT2 | |
| SCHEMBL377526 | 0.82 | ALDH1A1 (0.48) | ALDH1A1MAPTLMNAGPR119NPC1 | |
| SCHEMBL377867 | 0.82 | ALDH1A1 (0.48) | ALDH1A1MAPTLMNAGPR119NPC1 | |
| SCHEMBL6894620 | 0.81 | ALDH1A1 (0.59) | TDP1ALDH1A1MAPTLMNATP53 | |
| SCHEMBL26133849 | 0.80 | ALDH1A1 (0.49) | TDP1ALDH1A1MAPTLMNAHPGD | |
| SCHEMBL26548342 | 0.78 | TDP1 (0.47) | TDP1ALDH1A1MAPTLMNASIRT2 | |
| SCHEMBL377559 | 0.78 | ALDH1A1 (0.48) | ALDH1A1MAPTLMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230133132-A1 | NAMPT MODULATORS | CYTOKINETICS, INC. | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230133132-A1 | NAMPT MODULATORS | NAMPT, MC4R, SIRT1 | TDP1 4486/4885ALDH1A1 2019/4885MAPT 718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.