Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.30 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26135597 | 0.83 | SLC6A2 (0.38) | SLC6A4SLC6A3KDM4EPARP1 | |
| SCHEMBL2177879 | 0.65 | P2RX7 (0.37) | KDM4EPARP1 | |
| SCHEMBL2177883 | 0.65 | P2RX7 (0.37) | KDM4EPARP1 | |
| SCHEMBL1483488 | 0.63 | EPHX1 (0.37) | KDM4EPARP1 | |
| SCHEMBL27746280 | 0.62 | SLC6A2 (0.48) | SLC6A4SLC6A3 | |
| SCHEMBL18547313 | 0.62 | SLC6A4 (0.53) | SLC6A4SLC6A3 | |
| SCHEMBL21905026 | 0.61 | — | — | |
| SCHEMBL7833643 | 0.61 | FFAR2 (0.39) | KDM4EPARP1 | |
| SCHEMBL2431567 | 0.59 | P2RX7 (0.36) | KDM4E | |
| SCHEMBL2168915 | 0.59 | NAALAD2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023185073-A1 | PARP7 INHIBITOR AND USE THEREOF | 诺沃斯达药业(上海)有限公司 | 2023-10-05 | — | — | WO | disclosed |