Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 2/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1483488 | 0.78 | EPHX1 (0.37) | P2RX7ALDH1A1ALOX5MKNK1MKNK2 | |
| SCHEMBL15061182 | 0.73 | FFAR2 (0.42) | FFAR2LMNAPTGER3 | |
| SCHEMBL2177883 | 0.71 | P2RX7 (0.37) | P2RX7LMNATSHRALDH1A1MKNK1 | |
| SCHEMBL2177879 | 0.71 | P2RX7 (0.37) | P2RX7LMNATSHRALDH1A1MKNK1 | |
| SCHEMBL4651196 | 0.70 | PDPK1 (0.39) | FFAR2PTGER3ALDH1A1ALOX5KDM4E | |
| SCHEMBL18128788 | 0.69 | ADORA3 (0.44) | FFAR2LMNATSHRALDH1A1KDM4E | |
| SCHEMBL2431567 | 0.69 | P2RX7 (0.36) | P2RX7LMNAALDH1A1KDM4EHTT | |
| SCHEMBL29106359 | 0.69 | LMNA (0.37) | P2RX7LMNATSHRALDH1A1ALOX5 | |
| SCHEMBL28909154 | 0.69 | FFAR2 (0.47) | FFAR2ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL6501464 | 0.69 | ADORA1 (0.50) | TSHRALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1080092-A2 | BICYCLIC PYRIMIDINES AND BICYCLIC 3,4-DIHYDROPYRIMIDINES AS INHIBITORS OF CELLULAR PROLIFERATION | WARNER-LAMBERT COMPANY (US) | 2001-03-07 | — | — | EP | disclosed |
| WO-1999061444-A2 | BICYCLIC PYRIMIDINES AND BICYCLIC 3,4-DIHYDROPYRIMIDINES AS INHIBITORS OF CELLULAR PROLIFERATION | WARNER-LAMBERT COMPANY (US) | 1999-12-02 | — | — | WO | disclosed |