Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.55 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.52 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.52 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.52 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.52 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.52 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.52 |
| ▸ | GABRP | O00591 | 2/20 | 0.52 |
| ▸ | GABRD | O14764 | 2/20 | 0.52 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.52 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.52 |
| ▸ | GABRE | P78334 | 2/20 | 0.52 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.52 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.52 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.52 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.52 |
| ▸ | CCKBR | P32239 | 6/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2615369 | 1.00 | OPRK1 (0.55) | OPRK1LMNAPDE3AGABRA1GABRG2 | |
| SCHEMBL2615367 | 0.92 | LMNA (0.45) | OPRK1LMNAPDE3AGABRA1GABRG2 | |
| SCHEMBL11464860 | 0.87 | OPRK1 (0.55) | OPRK1LMNAPDE3AGABRA1GABRG2 | |
| SCHEMBL13284572 | 0.86 | OPRK1 (0.74) | OPRK1LMNAPDE3AGABRA1GABRG2 | |
| SCHEMBL4819989 | 0.86 | GABRA1 (0.72) | OPRK1LMNAPDE3AGABRA1GABRG2 | |
| SCHEMBL11339291 | 0.85 | OPRK1 (0.76) | OPRK1LMNAPDE3AGABRA1GABRG2 | |
| SCHEMBL2922460 | 0.85 | GABRA1 (0.55) | OPRK1LMNAPDE3AGABRA1GABRG2 | |
| SCHEMBL2920548 | 0.85 | GABRA1 (0.55) | OPRK1LMNAPDE3AGABRA1GABRG2 | |
| SCHEMBL2923658 | 0.85 | GABRA1 (0.55) | OPRK1LMNAPDE3AGABRA1GABRG2 | |
| SCHEMBL11287064 | 0.85 | OPRK1 (0.76) | OPRK1LMNAPDE3AGABRA1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120095217-A1 | FLUORINE CONTAINING COMPOUNDS AND METHODS OF USE THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095217-A1 | FLUORINE CONTAINING COMPOUNDS AND METHODS OF USE THEREOF | FLI1, CDC73, FOS | OPRK1 2388/4885LMNA 1375/4885PDE3A 2933/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.