Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 9/20 | 0.70 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.70 |
| ▸ | DRD2 | P14416 | 5/20 | 0.70 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.70 |
| ▸ | HTR1A | P08908 | 3/20 | 0.70 |
| ▸ | HTR2A | P28223 | 3/20 | 0.70 |
| ▸ | DRD3 | P35462 | 3/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.70 |
| ▸ | MLNR | O43193 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | PGR | P06401 | 2/20 | 0.70 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.70 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.70 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.70 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.70 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.70 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.70 |
| ▸ | DRD1 | P21728 | 2/20 | 0.70 |
| ▸ | DRD4 | P21917 | 2/20 | 0.70 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13285211 | 0.95 | DRD2 (0.77) | OPRM1CHRM1DRD2KCNH2HTR1A | |
| SCHEMBL2615401 | 0.92 | DRD2 (0.75) | OPRM1CHRM1DRD2KCNH2HTR1A | |
| SCHEMBL2615398 | 0.92 | DRD2 (0.75) | OPRM1CHRM1DRD2KCNH2HTR1A | |
| SCHEMBL1152218 | 0.91 | OPRM1 (0.76) | OPRM1CHRM1DRD2KCNH2HTR1A | |
| SCHEMBL10034840 | 0.88 | OPRM1 (0.91) | OPRM1CHRM1DRD2KCNH2HTR1A | |
| Isopropyl Alcohol SCHEMBL11845667 | 0.88 | OPRM1 (0.71) | OPRM1CHRM1DRD2KCNH2HTR1A | |
| SCHEMBL1152828 | 0.87 | DRD2 (0.81) | OPRM1CHRM1DRD2KCNH2HTR1A | |
| SCHEMBL2615400 | 0.87 | DRD2 (0.81) | OPRM1CHRM1DRD2KCNH2HTR1A | |
| Isopropyl Alcohol SCHEMBL11846805 | 0.84 | OPRM1 (0.68) | OPRM1CHRM1DRD2KCNH2HTR1A | |
| SCHEMBL1152823 | 0.83 | DRD2 (0.76) | OPRM1CHRM1DRD2KCNH2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120095217-A1 | FLUORINE CONTAINING COMPOUNDS AND METHODS OF USE THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095217-A1 | FLUORINE CONTAINING COMPOUNDS AND METHODS OF USE THEREOF | FLI1, CDC73, FOS | OPRM1 2013/4885CHRM1 4388/4885DRD2 2857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.