Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 8/20 | 0.91 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.91 |
| ▸ | HTR1A | P08908 | 3/20 | 0.91 |
| ▸ | DRD2 | P14416 | 3/20 | 0.91 |
| ▸ | HTR2A | P28223 | 3/20 | 0.91 |
| ▸ | DRD3 | P35462 | 3/20 | 0.91 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.91 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.91 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.91 |
| ▸ | MLNR | O43193 | 2/20 | 0.91 |
| ▸ | LMNA | P02545 | 2/20 | 0.91 |
| ▸ | PGR | P06401 | 2/20 | 0.91 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.91 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.91 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.91 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.91 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.91 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.91 |
| ▸ | DRD1 | P21728 | 2/20 | 0.91 |
| ▸ | DRD4 | P21917 | 2/20 | 0.91 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pimozide SCHEMBL14127068 | 0.95 | DRD2 (1.00) | OPRM1CHRM1HTR1ADRD2HTR2A | |
| Pimozide SCHEMBL41584 | 0.95 | DRD2 (1.00) | OPRM1CHRM1HTR1ADRD2HTR2A | |
| Pimozide SCHEMBL29381325 | 0.95 | DRD2 (1.00) | OPRM1CHRM1HTR1ADRD2HTR2A | |
| Pimozide SCHEMBL572869 | 0.94 | DRD2 (0.98) | OPRM1CHRM1HTR1ADRD2HTR2A | |
| SCHEMBL12863786 | 0.94 | DRD2 (0.98) | OPRM1CHRM1HTR1ADRD2HTR2A | |
| Pimozide SCHEMBL29031811 | 0.94 | DRD2 (0.98) | OPRM1CHRM1HTR1ADRD2HTR2A | |
| SCHEMBL2615401 | 0.91 | DRD2 (0.75) | OPRM1CHRM1HTR1ADRD2HTR2A | |
| SCHEMBL2615398 | 0.91 | DRD2 (0.75) | OPRM1CHRM1HTR1ADRD2HTR2A | |
| Pimozide SCHEMBL14894944 | 0.90 | DRD2 (0.89) | OPRM1CHRM1HTR1ADRD2HTR2A | |
| SCHEMBL1152218 | 0.90 | OPRM1 (0.76) | OPRM1CHRM1HTR1ADRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230126987-A1 | METHODS FOR TREATING CYTOKINE STORM SYNDROME AND RELATED DISEASES | GENEROS BIOPHARMA LTD. (KY) | 2023-04-27 | — | — | US | disclosed |
| US-20170050929-A1 | AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF IN TREATING AUTOPHAGY ASSOCIATED DISEASES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2017-02-23 | — | — | US | disclosed |
| US-20140066439-A1 | OSTEOCLAST ACTIVITY | Katholieke Universiteit Leuen, K.U.Leuven R&D (BE) | 2014-03-06 | — | — | US | disclosed |
| US-20120077705-A1 | Methods for Identifying Autophagy Inducing Compounds | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-03-29 | — | — | US | disclosed |
| US-20100267704-A1 | Autophagy Inducing Compounds and Uses Thereof in Treating Autophagy Associated Diseases | President an Fellows of Harvard Colege (US) | 2010-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140066439-A1 | OSTEOCLAST ACTIVITY | CTSA, SQSTM1, BECN1 | OPRM1 1958/4885CHRM1 1319/4885HTR1A 4648/4885 |
| US-20230126987-A1 | METHODS FOR TREATING CYTOKINE STORM SYNDROME AND RELATED DISEASES | IL6, IL2, IL15 | OPRM1 3807/4885CHRM1 4657/4885HTR1A 3087/4885 |
| US-20170050929-A1 | AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF IN TREATING AUTOPHAGY ASSOCIATED DISEASES | BECN1, ATG7, SQSTM1 | OPRM1 4332/4885CHRM1 4769/4885HTR1A 3673/4885 |
| US-20100267704-A1 | Autophagy Inducing Compounds and Uses Thereof in Treating Autophagy Associated Diseases | SQSTM1, ATG7, BECN1 | OPRM1 4458/4885CHRM1 4787/4885HTR1A 3736/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.