SCHEMBL26154061

SCHEMBL26154061

COc1ccccc1NC(=S)Nc1ccc(C2CCCC2)cc1

nearest known ligand 0.61

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.61
▸ NPSR1 Q6W5P4 1/20 0.61
▸ SMN1; SMN2 Q16637 3/20 0.57
▸ HPGD P15428 2/20 0.57
▸ GAA P10253 4/20 0.54
▸ ALDH1A1 P00352 3/20 0.54
▸ MAPT P10636 2/20 0.54
▸ KDM4E B2RXH2 1/20 0.54
▸ THRB P10828 1/20 0.51
▸ ALOX12 P18054 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17956756 0.80 GAA (0.71) LMNASMN1; SMN2HPGDGAAALDH1A1
SCHEMBL25517519 0.79 HPGD (0.63) LMNASMN1; SMN2HPGDGAAALDH1A1
SCHEMBL31388324 0.78 HPGD (0.80) LMNANPSR1SMN1; SMN2HPGDGAA
SCHEMBL3822985 0.78 HPGD (0.80) LMNANPSR1SMN1; SMN2HPGDGAA
SCHEMBL7945600 0.78 ALDH1A1 (0.62) LMNASMN1; SMN2HPGDGAAALDH1A1
SCHEMBL6816152 0.77 KMT2A (0.71) LMNASMN1; SMN2HPGDGAAALDH1A1
SCHEMBL5458347 0.74 RAB9A (0.61) LMNANPSR1SMN1; SMN2HPGDALDH1A1
SCHEMBL7945596 0.74 SMN1; SMN2 (0.76) LMNASMN1; SMN2HPGDGAAALDH1A1
SCHEMBL3307714 0.73 RAB9A (0.60) LMNANPSR1SMN1; SMN2HPGDALDH1A1
SCHEMBL3307712 0.73 RAB9A (0.60) LMNANPSR1SMN1; SMN2HPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230157996-A1 SMALL-MOLECULE INHIBITOR TARGETING EB VIRUS NUCLEAR ANTIGEN PROTEIN, PREPARATION METHOD AND USE THEREOF Shenzhen Bay Laboratory (CN) 2023-05-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230157996-A1 SMALL-MOLECULE INHIBITOR TARGETING EB VIRUS NUCLEAR ANTIGEN PROTEIN, PREPARATION METHOD AND USE THEREOF SSB, EBNA1BP2, PML LMNA 822/4885NPSR1 4384/4885SMN1; SMN2 2894/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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