Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13785293 | 0.93 | PRKCA (0.38) | CYP4F2CYP4A11ALDH1A1TSHRPRKCA | |
| SCHEMBL12191433 | 0.92 | TSHR (0.35) | CYP4F2CYP4A11ALDH1A1TSHRTP53 | |
| SCHEMBL2615570 | 0.92 | CYP4F2 (0.33) | CYP4F2CYP4A11ALDH1A1TSHRTP53 | |
| SCHEMBL15256708 | 0.92 | TSHR (0.35) | CYP4F2CYP4A11ALDH1A1TSHRTP53 | |
| SCHEMBL2615566 | 0.92 | CYP4F2 (0.33) | CYP4F2CYP4A11ALDH1A1TSHRTP53 | |
| SCHEMBL12752002 | 0.92 | TSHR (0.35) | CYP4F2CYP4A11ALDH1A1TSHRTP53 | |
| SCHEMBL10786936 | 0.90 | ALDH1A1 (0.52) | CYP4F2CYP4A11ALDH1A1TSHRHSD17B10 | |
| SCHEMBL12751971 | 0.86 | ALDH1A1 (0.40) | CYP4F2CYP4A11ALDH1A1TSHRTP53 | |
| SCHEMBL29141593 | 0.86 | THRB (0.38) | CYP4F2CYP4A11THRB | |
| SCHEMBL12752001 | 0.86 | TSHR (0.40) | CYP4F2CYP4A11ALDH1A1TSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9249275-B2 | Polyionic dendrimer and hydrogel comprising same | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2016-02-02 | — | — | US | disclosed |
| US-9249275-B2 | Polyionic dendrimer and hydrogel comprising same | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2016-02-02 | — | — | US | disclosed |
| US-20140221292-A1 | POLYIONIC DENDRIMER AND HYDROGEL COMPRISING SAME | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2014-08-07 | — | — | US | disclosed |
| US-20140221292-A1 | POLYIONIC DENDRIMER AND HYDROGEL COMPRISING SAME | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2014-08-07 | — | — | US | disclosed |
| US-20120101041-A1 | POLYIONIC DENDRIMER AND HYDROGEL COMPRISING SAME | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2012-04-26 | — | — | US | disclosed |
| US-20120101041-A1 | POLYIONIC DENDRIMER AND HYDROGEL COMPRISING SAME | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221292-A1 | POLYIONIC DENDRIMER AND HYDROGEL COMPRISING SAME | CD44, PCNA, GMNN | CYP4F2 4690/4885CYP4A11 4711/4885ALDH1A1 2155/4885 |
| US-20120101041-A1 | POLYIONIC DENDRIMER AND HYDROGEL COMPRISING SAME | CD44, PCNA, GMNN | CYP4F2 4690/4885CYP4A11 4711/4885ALDH1A1 2155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.