SCHEMBL2615570

SCHEMBL2615570

CC(CO)(CO)C(=O)OCC(C)(COC(=O)C(C)(CO)CO)C(=O)OCC(C)(COC(=O)C(C)(COC(=O)C(C)(CO)CO)COC(=O)C(C)(CO)CO)C(=O)OCCOCCOC(=O)C(C)(COC(=O)C(C)(COC(=O)C(C)(CO)CO)COC(=O)C(C)(CO)CO)COC(=O)C(C)(COC(=O)C(C)(CO)CO)COC(=O)C(C)(CO)CO

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.33
CYP4A11 Q02928 1/20 0.33
ALDH1A1 P00352 3/20 0.32
TSHR P16473 3/20 0.32
TP53 P04637 2/20 0.32
HIF1A Q16665 2/20 0.32
HSD17B10 Q99714 1/20 0.32
THRB P10828 1/20 0.32
PRKCA P17252 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2615566 1.00 CYP4F2 (0.33) CYP4F2CYP4A11ALDH1A1TSHRTP53
SCHEMBL13785294 0.94 PRKCA (0.33) PRKCA
SCHEMBL29141593 0.93 THRB (0.38) CYP4F2CYP4A11THRB
SCHEMBL12191440 0.93 TSHR (0.32) CYP4F2CYP4A11TSHR
SCHEMBL2615569 0.92 CYP4F2 (0.37) CYP4F2CYP4A11ALDH1A1TSHRTP53
SCHEMBL17531342 0.92 THRB (0.37) THRB
SCHEMBL12628128 0.91 THRB (0.39) THRB
SCHEMBL12395012 0.90 ALDH1A1 (0.44) CYP4F2CYP4A11ALDH1A1TSHRTHRB
SCHEMBL12589090 0.87 THRB (0.32) CYP4F2CYP4A11THRB
SCHEMBL14448141 0.87 PRKCA (0.33) THRBPRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9249275-B2 Polyionic dendrimer and hydrogel comprising same JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2016-02-02 US disclosed
US-9249275-B2 Polyionic dendrimer and hydrogel comprising same JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2016-02-02 US disclosed
US-20140221292-A1 POLYIONIC DENDRIMER AND HYDROGEL COMPRISING SAME JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2014-08-07 US disclosed
US-20140221292-A1 POLYIONIC DENDRIMER AND HYDROGEL COMPRISING SAME JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2014-08-07 US disclosed
US-20120101041-A1 POLYIONIC DENDRIMER AND HYDROGEL COMPRISING SAME JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2012-04-26 US disclosed
US-20120101041-A1 POLYIONIC DENDRIMER AND HYDROGEL COMPRISING SAME JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2012-04-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140221292-A1 POLYIONIC DENDRIMER AND HYDROGEL COMPRISING SAME CD44, PCNA, GMNN CYP4F2 4690/4885CYP4A11 4711/4885ALDH1A1 2155/4885
US-20120101041-A1 POLYIONIC DENDRIMER AND HYDROGEL COMPRISING SAME CD44, PCNA, GMNN CYP4F2 4690/4885CYP4A11 4711/4885ALDH1A1 2155/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.