Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL426634 | 0.93 | CTSL (0.41) | SYKFFAR1CTSLCTSSCTSK | |
| SCHEMBL426645 | 0.86 | HRH4 (0.44) | SYKCTSLCTSSCTSKACHE | |
| SCHEMBL26157155 | 0.84 | TLR9 (0.41) | TLR9TLR8TLR7KDM2BKCNH2 | |
| SCHEMBL16453463 | 0.82 | CRHR1 (0.43) | FFAR1ACACB | |
| SCHEMBL427054 | 0.79 | HRH3 (0.44) | — | |
| SCHEMBL16453522 | 0.79 | MEN1 (0.48) | FFAR1ACACB | |
| SCHEMBL23205103 | 0.79 | TLR9 (0.38) | TLR9TLR8TLR7KDM2BKCNH2 | |
| SCHEMBL23205104 | 0.79 | TLR9 (0.38) | TLR9TLR8TLR7KDM2BKCNH2 | |
| SCHEMBL16453456 | 0.78 | NPC1 (0.50) | FFAR1 | |
| SCHEMBL450035 | 0.77 | CTSS (0.41) | SYKCTSLCTSSCTSKBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023093728-A1 | BRM SELECTIVE DEGRADATION AGENT COMPOUND AND USE THEREOF | 江苏先声药业有限公司 | 2023-06-01 | — | — | WO | disclosed |