Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9506612 | 0.71 | NR1H2 (0.31) | — | |
| SCHEMBL441396 | 0.67 | — | — | |
| SCHEMBL9507326 | 0.65 | — | — | |
| SCHEMBL27580168 | 0.65 | — | — | |
| SCHEMBL27098286 | 0.65 | — | — | |
| SCHEMBL4634129 | 0.65 | — | — | |
| SCHEMBL15863920 | 0.63 | — | — | |
| SCHEMBL29501847 | 0.63 | — | — | |
| SCHEMBL8926659 | 0.61 | — | — | |
| SCHEMBL14727437 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119613425-A | Synthesis method of curved Bei Ti fixed five-ring core skeleton | 南方科技大学 | 2025-03-14 | — | — | CN | claimed |
| CN-118994019-A | Process for the preparation of (R) -2- ((R) -2' -amino-4 ',5' -dihydro-1 ' H-imidazol-4 ' -yl) -6-methylhept-5-enoate derivatives | 临沂大学 | 2024-11-22 | — | — | CN | claimed |
| US-20250250226-A1 | IONIZABLE COMPOUNDS AND COMPOSITIONS AND USES THEREOF | NITTO DENKO CORP (JP) | 2025-08-07 | — | — | US | disclosed |
| WO-2025124429-A1 | AROMATIC AMINE COMPOUND, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 北京康辰药业股份有限公司 | 2025-06-19 | — | — | WO | disclosed |
| US-12319643-B2 | Ionizable compounds and compositions and uses thereof | NITTO DENKO CORPORATION (JP) | 2025-06-03 | — | — | US | disclosed |
| CN-119930618-A | Polysubstituted aryl derivative and preparation method and application thereof | 浙江海正药业股份有限公司 | 2025-05-06 | — | — | CN | disclosed |
| WO-2025077773-A1 | NOVEL TYPE I TOPOISOMERASE INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翊维康医药有限责任公司 | 2025-04-17 | — | — | WO | disclosed |
| CN-119613425-A | Synthesis method of curved Bei Ti fixed five-ring core skeleton | 南方科技大学 | 2025-03-14 | — | — | CN | disclosed |
| CN-119546585-A | Preparation, application and application of indole compound | 上海济煜医药科技有限公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-119264153-A | Substituted tricyclic derivatives, pharmaceutical compositions and uses thereof | 上海海雁医药科技有限公司 | 2025-01-07 | — | — | CN | disclosed |
| CN-119192175-A | Compound, pharmaceutical composition and application thereof | 北京康辰药业股份有限公司 | 2024-12-27 | — | — | CN | disclosed |
| EP-3313449-A1 | IONIZABLE COMPOUNDS AND COMPOSITIONS AND USES THEREOF | Nitto Denko Corporation (JP) | 2018-05-02 | — | — | EP | disclosed |
| CN-107708739-A | Ionizable compound, composition and their purposes | 日东电工株式会社 | 2018-02-16 | — | — | CN | disclosed |
| WO-2017120429-A1 | SELECTIVE INHIBITORS OF CLINICALLY IMPORTANT MUTANTS OF THE EGFR TYROSINE KINASE | CS Pharmasciences, Inc. (US) | 2017-07-13 | — | — | WO | disclosed |
| WO-2016210190-A1 | IONIZABLE COMPOUNDS AND COMPOSITIONS AND USES THEREOF | NITTO DENKO CORPORATION (JP) | 2016-12-29 | — | — | WO | disclosed |
| US-20160376229-A1 | IONIZABLE COMPOUNDS AND COMPOSITIONS AND USES THEREOF | NITTO DENKO CORPORATION (JP) | 2016-12-29 | — | — | US | disclosed |
| US-8163919-B2 | Imidazopyridinyl benzamide mitotic kinesin inhibitors | CYTOKINETICS, INCORPORATED (US) | 2012-04-24 | — | — | US | disclosed |
| US-20090306127-A1 | Certain Chemical Entities, Compositions and Methods | CYTOKINETICS, INC | 2009-12-10 | — | — | US | disclosed |
| EP-0745073-B1 | 5-SUBSTITUTED DERIVATIVES OF MYCOPHENOLIC ACID | SYNTEX INC (US) | 2000-07-12 | — | — | EP | disclosed |
| CN-1030918-C | 4-substituted alkyl carbapenem antibiotics | BRISTOL MYERS SQUIBB CO (US) | 1996-02-07 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250250226-A1 | IONIZABLE COMPOUNDS AND COMPOSITIONS AND USES THEREOF | NCL, RNASE1, RNMT | ALDH1A1 3118/4885MAPK1 4311/4885TDP1 1223/4885 |
| US-20160376229-A1 | IONIZABLE COMPOUNDS AND COMPOSITIONS AND USES THEREOF | NCL, CHMP4B, RNASE1 | ALDH1A1 3075/4885MAPK1 4553/4885TDP1 1220/4885 |
| US-20090306127-A1 | Certain Chemical Entities, Compositions and Methods | KIF5B, KIF2C, PLK1 | ALDH1A1 1977/4885MAPK1 2332/4885TDP1 231/4885 |
| US-12319643-B2 | Ionizable compounds and compositions and uses thereof | NCL, RNASE1, RNMT | ALDH1A1 3118/4885MAPK1 4311/4885TDP1 1223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.