Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25399580 | 0.95 | CYP1A2 (0.55) | CYP1A2CYP2C19CYP2D6RAB9ASMN1; SMN2 | |
| SCHEMBL99433 | 0.94 | TDP1 (0.55) | CYP1A2CYP2C19CYP2D6RAB9ASMN1; SMN2 | |
| SCHEMBL10318724 | 0.82 | ACHE (0.54) | — | |
| SCHEMBL10458108 | 0.76 | CYP1A2 (1.00) | CYP1A2CYP2C19CYP2D6RAB9ASMN1; SMN2 | |
| SCHEMBL4351612 | 0.75 | TDP1 (0.66) | CYP1A2CYP2C19CYP2D6RAB9ASMN1; SMN2 | |
| SCHEMBL6790333 | 0.75 | TDP1 (0.71) | CYP1A2CYP2C19CYP2D6RAB9ASMN1; SMN2 | |
| SCHEMBL1856372 | 0.75 | CYP1A2 (0.65) | CYP1A2CYP2C19CYP2D6CHRM2MEN1 | |
| SCHEMBL10037241 | 0.74 | GAA (0.54) | CYP1A2RAB9ASMN1; SMN2NPC1CASP3 | |
| SCHEMBL8442261 | 0.74 | MMP2 (0.46) | CYP1A2CYP2C19CYP2D6RAB9ASMN1; SMN2 | |
| SCHEMBL2604742 | 0.73 | TDP1 (0.75) | CYP1A2CYP2C19TDP1L3MBTL1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250263385-A1 | \"Good\" buffer-based cationic lipids | SANOFI (FR) | 2025-08-21 | — | — | US | disclosed |
| EP-4508039-A1 | GOOD\" BUFFER-BASED CATIONIC LIPIDS | Sanofi (FR) | 2025-02-19 | — | — | EP | disclosed |
| WO-2023198857-A9 | \"GOOD\" BUFFER-BASED CATIONIC LIPIDS | SANOFI (FR) | 2025-02-06 | — | — | WO | disclosed |
| WO-2023198857-A1 | \"GOOD\" BUFFER-BASED CATIONIC LIPIDS | SANOFI (FR) | 2023-10-19 | — | — | WO | disclosed |
| WO-2023198857-A1 | \"GOOD\" BUFFER-BASED CATIONIC LIPIDS | SANOFI (FR) | 2023-10-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250263385-A1 | \"Good\" buffer-based cationic lipids | NPC1L1, CETP, LIPA | CYP1A2 4260/4885CYP2C19 3708/4885CYP2D6 4597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.