Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL99433 | 0.98 | TDP1 (0.55) | CYP1A2CYP2D6CYP2C19TDP1L3MBTL1 | |
| SCHEMBL26186830 | 0.95 | CYP1A2 (0.60) | CYP1A2CYP2D6CYP2C19TDP1L3MBTL1 | |
| SCHEMBL10318724 | 0.83 | ACHE (0.54) | ACHE | |
| SCHEMBL6790333 | 0.78 | TDP1 (0.71) | CYP1A2CYP2D6CYP2C19TDP1L3MBTL1 | |
| SCHEMBL17266522 | 0.76 | CYP1A2 (0.90) | CYP1A2CYP2D6CYP2C19TDP1L3MBTL1 | |
| SCHEMBL8862878 | 0.76 | TDP1 (0.75) | CYP1A2CYP2C19TDP1L3MBTL1ACHE | |
| SCHEMBL6777483 | 0.76 | TDP1 (0.75) | CYP1A2CYP2C19TDP1L3MBTL1ACHE | |
| SCHEMBL8863154 | 0.76 | TDP1 (0.75) | CYP1A2CYP2C19TDP1L3MBTL1ACHE | |
| SCHEMBL2604742 | 0.76 | TDP1 (0.75) | CYP1A2CYP2C19TDP1L3MBTL1ACHE | |
| SCHEMBL8862728 | 0.76 | TDP1 (0.75) | CYP1A2CYP2C19TDP1L3MBTL1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260021055-A1 | Asymmetric Piperazine-Based Cationic Lipids | TRANSLATE BIO, INC. (US) | 2026-01-22 | — | — | US | disclosed |
| WO-2023178167-A1 | ASYMMETRIC PIPERAZINE-BASED CATIONIC LIPIDS | TRANSLATE BIO, INC. (US) | 2023-09-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260021055-A1 | Asymmetric Piperazine-Based Cationic Lipids | SGMS2, SPTLC2, SGMS1 | CYP1A2 3267/4885CYP2D6 3781/4885CYP2C19 4501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.