Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.61 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | AHCY | P23526 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | PNP | P00491 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.56 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | ADA | P00813 | 1/20 | 0.55 |
| ▸ | DPP4 | P27487 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.53 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.53 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.53 |
| ▸ | GAPDH | P04406 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12352424 | 1.00 | POLB (0.62) | POLBENPP1P2RY1HIF1AAHCY | |
| SCHEMBL14639883 | 1.00 | POLB (0.62) | POLBENPP1P2RY1HIF1AAHCY | |
| SCHEMBL12837026 | 1.00 | POLB (0.62) | POLBENPP1P2RY1HIF1AAHCY | |
| Deoxyadenosine SCHEMBL27603573 | 0.89 | HIF1A (0.72) | POLBENPP1P2RY1HIF1ASMN1; SMN2 | |
| SCHEMBL23547685 | 0.89 | POLB (0.63) | POLBENPP1P2RY1HIF1AAHCY | |
| Deoxyadenosine SCHEMBL19877 | 0.89 | HIF1A (0.71) | POLBENPP1P2RY1HIF1ASMN1; SMN2 | |
| Deoxyadenosine SCHEMBL193181 | 0.89 | HIF1A (0.71) | POLBENPP1P2RY1HIF1ASMN1; SMN2 | |
| Deoxyadenosine SCHEMBL5182039 | 0.89 | HIF1A (0.71) | POLBENPP1P2RY1HIF1ASMN1; SMN2 | |
| Deoxyadenosine SCHEMBL21637036 | 0.89 | HIF1A (0.71) | POLBENPP1P2RY1HIF1ASMN1; SMN2 | |
| Deoxyadenosine SCHEMBL23982174 | 0.89 | HIF1A (0.71) | POLBENPP1P2RY1HIF1ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242569-A1 | PHOSPHOROUS (V)-BASED REAGENTS, PROCESSES FOR THE PREPARATION THEREOF, AND THEIR USE IN MAKING STEREO-DEFINED ORGANOPHOSHOROUS (V) COMPOUNDS | THE SCRIPPS RESEARCH INSTITUTE | 2023-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242569-A1 | PHOSPHOROUS (V)-BASED REAGENTS, PROCESSES FOR THE PREPARATION THEREOF, AND THEIR USE IN MAKING STEREO-DEFINED ORGANOPHOSHOROUS (V) COMPOUNDS | PPIP5K2, INPP5B, PTMS | POLB 1692/4885ENPP1 104/4885P2RY1 799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.