Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COL1A1 | P02452 | 4/20 | 0.67 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.67 |
| ▸ | ACHE | P22303 | 12/20 | 0.65 |
| ▸ | BCHE | P06276 | 10/20 | 0.65 |
| ▸ | PREP | P48147 | 10/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | RAD52 | P43351 | 2/20 | 0.61 |
| ▸ | EP300 | Q09472 | 2/20 | 0.61 |
| ▸ | KDM1A | O60341 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26192141 | 0.89 | COL1A1 (0.68) | COL1A1NR1H4ACHEBCHEPREP | |
| SCHEMBL26192504 | 0.89 | ACHE (0.62) | COL1A1NR1H4ACHEBCHEPREP | |
| SCHEMBL26291523 | 0.82 | ACHE (0.64) | COL1A1NR1H4ACHEBCHEPREP | |
| SCHEMBL26192808 | 0.79 | ACHE (0.70) | COL1A1NR1H4ACHEBCHEPREP | |
| SCHEMBL910108 | 0.79 | BCHE (1.00) | ACHEBCHEPREP | |
| SCHEMBL26192506 | 0.78 | RAC1 (0.62) | COL1A1NR1H4ACHEBCHEKDM4E | |
| SCHEMBL27147420 | 0.77 | CYP3A4 (0.85) | COL1A1NR1H4ACHEBCHEKDM4E | |
| Palmitine SCHEMBL562120 | 0.77 | CYP3A4 (1.00) | COL1A1NR1H4ACHEBCHEKDM4E | |
| Palmitine SCHEMBL29471136 | 0.77 | CYP3A4 (1.00) | COL1A1NR1H4ACHEBCHEKDM4E | |
| Palmitine SCHEMBL29350054 | 0.77 | CYP3A4 (1.00) | COL1A1NR1H4ACHEBCHEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230271982-A1 | CODRUG THAT DISINTEGRATES IN INTESTINE, PREPARATION THEREFOR, AND USE THEREOF | SHANGHAI ENNOVABIO PHARMACEUTICALS CO., LTD. (CN) | 2023-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230271982-A1 | CODRUG THAT DISINTEGRATES IN INTESTINE, PREPARATION THEREFOR, AND USE THEREOF | VIP, SI, PDCD5 | COL1A1 3111/4885NR1H4 22/4885ACHE 764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.