Propiram

Propiram

SCHEMBL26193

CCC(=O)N(c1ccccn1)C(C)CN1CCCCC1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
HTR1A P08908 1/20 0.52
ACHE P22303 1/20 0.48
OPRM1 P35372 10/20 0.47
SIGMAR1 Q99720 1/20 0.42
ALDH1A1 P00352 1/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propiram SCHEMBL38655379 1.00 MEN1 (0.52) MEN1KMT2AHTR1AACHEOPRM1
Propiram SCHEMBL3093165 0.99 MEN1 (0.52) MEN1KMT2AHTR1AACHEOPRM1
Propiram SCHEMBL29725982 0.94 MEN1 (0.48) MEN1KMT2AHTR1AACHEOPRM1
Propiram SCHEMBL11079155 0.94 MEN1 (0.48) MEN1KMT2AHTR1AACHEOPRM1
Propiram SCHEMBL592478 0.94 MEN1 (0.48) MEN1KMT2AHTR1AACHEOPRM1
SCHEMBL26930970 0.85 OPRM1 (0.43) MEN1KMT2AHTR1AOPRM1SIGMAR1
Phenampromide SCHEMBL907884 0.81 OPRM1 (0.47) MEN1KMT2AOPRM1ALDH1A1
Phenampromide SCHEMBL907886 0.81 OPRM1 (0.47) MEN1KMT2AOPRM1ALDH1A1
Phenampromide SCHEMBL11661873 0.80 ALDH1A1 (0.49) MEN1KMT2AOPRM1ALDH1A1
Phenampromide SCHEMBL11661877 0.80 ALDH1A1 (0.49) MEN1KMT2AOPRM1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7972 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250319074-A1 TREATMENT AND MANAGEMENT OF AUGMENTATION IN RESTLESS LEGS SYNDROME UNIV EAST CAROLINA (US) 2025-10-16 US claimed
US-12383743-B2 Treatment of addiction and dependency TACA JR ARTURO C (US) 2025-08-12 US claimed
US-20250228771-A1 ALKALINE INTRAORAL PRODUCTS EMPLICURE AB (publ) (SE) 2025-07-17 US claimed
EP-4581017-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS Biodol Therapeutics (FR) 2025-07-09 EP claimed
EP-4565202-A1 ALKALINE INTRAORAL PRODUCTS EMPLICURE AB (publ) (SE) 2025-06-11 EP claimed
EP-4561699-A1 SELECTIVE OPIOID RECEPTOR AGONISTS AND ANTAGONISTS The United States of America, as represented by the Secretary, Department of Health and Human Services (US) 2025-06-04 EP claimed
US-12133922-B2 Abuse resistant capsule R.P. SCHERER TECHNOLOGIES, LLC (US) 2024-11-05 US claimed
US-20240288374-A1 PLASMONIC NANOPARTICLE PLATFORM FOR ANALYTE DETECTION Zymeron Corporation 2024-08-29 US claimed
WO-2024172892-A1 PLASMONIC NANOPARTICLE PLATFORM FOR ANALYTE DETECTION Zymeron Corporation (US) 2024-08-22 WO claimed
EP-3768679-B1 BIASED POTENT OPIOID-LIKE AGONISTS AS IMPROVED MEDICATIONS TO TREAT CHRONIC AND ACUTE PAIN AND METHODS OF USING THE SAME US HEALTH (US) 2024-06-26 EP claimed
WO-1995014460-A1 OPIOID FORMULATIONS FOR TREATING PAIN EURO-CELTIQUE S.A. (LU) 1995-06-01 WO claimed
EP-0647448-A1 Orally administrable opioid formulations having extended duration of effect Euroceltique S.A. (LU) 1995-04-12 EP claimed
CN-1017211-B BAKING PROCESS FOR PEANUTS KOYO FOODS LTD (JP) 1992-07-01 CN claimed
CN-85101678-A Processing method and device thereof are fried in shallow oil in the roasting of peanut 1987-01-31 CN claimed
EP-0152379-A2 Process for preparing pharmaceutical compositions containing unilamellar liposomes CIBA-GEIGY AG (CH) 1985-08-21 EP claimed
US-4486436-A Analgesic and anti-inflammatory compositions comprising caffeine and methods of using same ANALGESIC ASSOCIATES (US) 1984-12-04 US claimed
US-4479956-A Analgesic compositions comprising propiram and methods of using same ANALGEIC ASSOCIATES (US) 1984-10-30 US claimed
US-4464376-A Analgesic and anti-inflammatory compositions comprising caffeine and methods of using same RICHARDSON-VICKS, INC. (US) 1984-08-07 US claimed
US-4126684-A 4-AMINO-3-P-HALOPHENYLBUTYRIC ACIDS AND THEIR DERIVATIVES USED IN THE CONTROL OF NARCOTIC ABUSE CIBA-GEIGY CORPORATION (US) 1978-11-21 US claimed
US-4070494-A Enteral pharmaceutical compositions BAYER AKTIENGESELLSCHAFT (DT) 1978-01-24 US claimed