Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 3/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17059141 | 0.82 | MEN1 (0.54) | HDAC3HDAC1ALDH1A1NFKB1KCNH2 | |
| SCHEMBL10294734 | 0.82 | KDM4E (0.57) | HDAC3HDAC1ALDH1A1NFKB1KCNH2 | |
| SCHEMBL10261106 | 0.80 | CA12 (0.49) | HDAC3HDAC1ALDH1A1NFKB1KCNH2 | |
| SCHEMBL10077477 | 0.80 | NFKB1 (0.60) | HDAC3HDAC1ALDH1A1NFKB1KCNH2 | |
| SCHEMBL18911291 | 0.76 | PTPN1 (0.54) | ALDH1A1SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL12266946 | 0.74 | KMT2A (0.58) | HDAC3HDAC1ALDH1A1NFKB1KCNH2 | |
| SCHEMBL2408925 | 0.73 | HDAC1 (0.56) | HDAC3HDAC1HDAC2 | |
| SCHEMBL10294776 | 0.73 | PLK1 (0.61) | SMN1; SMN2LMNANPC1RAB9AMAPT | |
| SCHEMBL958453 | 0.73 | MPO (0.55) | HDAC3HDAC1ALDH1A1CYP3A4BLM | |
| SCHEMBL23106506 | 0.73 | HPGD (0.60) | ALDH1A1KCNH2SMN1; SMN2LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3122757-B1 | CHARGED LINKERS AND THEIR USES FOR CONJUGATION | HANGZHOU DAC BIOTECH CO LTD (CN) | 2023-09-06 | — | — | EP | disclosed |