Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18911291 | 0.85 | PTPN1 (0.54) | MEN1KMT2AKDM4EHTTLMNA | |
| SCHEMBL17151163 | 0.84 | MEN1 (0.52) | MEN1KMT2AKDM4EHTTLMNA | |
| SCHEMBL19147527 | 0.84 | MEN1 (0.52) | MEN1KMT2AKDM4EHTTLMNA | |
| SCHEMBL17232572 | 0.84 | MEN1 (0.57) | MEN1KMT2AKDM4EHTTLMNA | |
| SCHEMBL26197859 | 0.82 | HDAC3 (0.46) | MEN1KMT2AKDM4ELMNARAB9A | |
| SCHEMBL11711682 | 0.78 | L3MBTL1 (0.66) | MEN1KMT2AKDM4EHTTLMNA | |
| SCHEMBL13652523 | 0.78 | RAB9A (0.58) | MEN1KMT2AKDM4EHTTLMNA | |
| SCHEMBL17072398 | 0.77 | KMT2A (0.54) | MEN1KMT2AKDM4EHTTLMNA | |
| SCHEMBL1230694 | 0.77 | ALDH1A1 (0.77) | MEN1KMT2AKDM4EHTTLMNA | |
| SCHEMBL17151069 | 0.77 | MEN1 (0.54) | MEN1KMT2AKDM4EHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170152274-A1 | CHARGED LINKERS AND THEIR USES FOR CONJUGATION | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2017-06-01 | — | — | US | disclosed |
| US-20150250896-A1 | HYDROPHILIC LINKERS AND THEIR USES FOR CONJUGATION OF DRUGS TO A CELL BINDING MOLECULES | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2015-09-10 | — | — | US | disclosed |
| WO-2015127685-A1 | CHARGED LINKERS AND THEIR USES FOR CONJUGATION | HANGZHOU DAC BIOTECH CO., LTD (CN) | 2015-09-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170152274-A1 | CHARGED LINKERS AND THEIR USES FOR CONJUGATION | PHOSPHO1, PCTP, CD2BP2 | MEN1 848/4885KMT2A 2177/4885KDM4E 3504/4885 |
| US-20150250896-A1 | HYDROPHILIC LINKERS AND THEIR USES FOR CONJUGATION OF DRUGS TO A CELL BINDING MOLECULES | CD44, EPCAM, ABCG2 | MEN1 2818/4885KMT2A 3452/4885KDM4E 4270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.