Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.45 |
| ▸ | MC5R | P33032 | 1/20 | 0.45 |
| ▸ | MC3R | P41968 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | THPO | P40225 | 2/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12085525 | 0.79 | MC4R (0.63) | MC4RMC5RMC3RSMN1; SMN2THPO | |
| SCHEMBL4266391 | 0.78 | ALDH1A1 (0.61) | HDAC6SMN1; SMN2ALDH1A1HIF1ALMNA | |
| SCHEMBL14036484 | 0.77 | LMNA (0.44) | HDAC6SMN1; SMN2ALDH1A1HIF1ALMNA | |
| SCHEMBL10874430 | 0.77 | CA12 (0.54) | MC4RMC5RMC3RHDAC6ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28679486 | 0.77 | ALDH1A1 (0.59) | HDAC6SMN1; SMN2ALDH1A1HIF1ALMNA | |
| SCHEMBL10151325 | 0.74 | CHRM2 (0.71) | MC4RMC5RMC3RSMN1; SMN2ALDH1A1 | |
| SCHEMBL7471448 | 0.74 | ALDH1A1 (0.56) | HDAC6SMN1; SMN2ALDH1A1HIF1ALMNA | |
| SCHEMBL12082968 | 0.74 | MC4R (0.58) | MC4RMC5RMC3RSMN1; SMN2THPO | |
| SCHEMBL12085625 | 0.74 | MAOA (0.59) | MC4RMC5RMC3RSMN1; SMN2LMNA | |
| SCHEMBL19456501 | 0.74 | MAOA (0.59) | MC4RMC5RMC3RSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230279476-A1 | NOVEL ACRYLATE DERIVATIVES AND USES THEREOF | EXPANSION TECHNOLOGIES (US) | 2023-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230279476-A1 | NOVEL ACRYLATE DERIVATIVES AND USES THEREOF | DCLRE1A, ACR, PHAX | MC4R 4732/4885MC5R 4744/4885MC3R 4670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.