Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22246017 | 0.84 | PTGS1 (0.37) | LTA4HDPP4MAPT | |
| SCHEMBL26200495 | 0.83 | LTA4H (0.33) | LTA4HDPP4MAPT | |
| SCHEMBL26200516 | 0.73 | ALDH1A1 (0.44) | MAPT | |
| SCHEMBL20518624 | 0.71 | LTA4H (0.52) | LTA4HDPP4MAPT | |
| SCHEMBL155897 | 0.71 | LTA4H (0.52) | LTA4HDPP4MAPT | |
| SCHEMBL22246009 | 0.68 | KMT2A (0.36) | LTA4HDPP4MAPT | |
| SCHEMBL22246046 | 0.67 | KMT2A (0.44) | MAPT | |
| SCHEMBL22246091 | 0.63 | PTGS1 (0.63) | — | |
| SCHEMBL22246047 | 0.58 | KMT2A (0.49) | — | |
| SCHEMBL19439597 | 0.58 | DAO (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11744826-B2 | Compounds and methods of treating retinal degeneration | CASE WESTERN RESERVE UNIVERSITY (US) | 2023-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11744826-B2 | Compounds and methods of treating retinal degeneration | ALDH1A2, PDE6D, PDE6C | LTA4H 486/4885DPP4 1504/4885MAPT 745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.