SCHEMBL26201214

SCHEMBL26201214

BOc1cc(C)c(C=Cc2c(C)cc(C)cc2C)c(C)c1

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 1/20 0.35
RAPGEF4 Q8WZA2 2/20 0.31
RAF1 P04049 2/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL699400 0.81 RAPGEF4 (0.43) ABCB1RAPGEF4RAF1HPGD
SCHEMBL699401 0.81 RAPGEF4 (0.43) ABCB1RAPGEF4RAF1HPGD
Ammonia Solution, Strong SCHEMBL1984066 0.78 RAPGEF4 (0.41) ABCB1RAPGEF4RAF1HPGD
SCHEMBL20054839 0.73 ALDH1A1 (0.46)
SCHEMBL26201193 0.72 PTGS1 (0.44)
SCHEMBL26201170 0.71 ABCB1 (0.31) ABCB1
SCHEMBL23458023 0.71 RAPGEF4 (0.39) ABCB1RAPGEF4HPGD
SCHEMBL23458022 0.71 RAPGEF4 (0.39) ABCB1RAPGEF4HPGD
SCHEMBL16788923 0.68 ABCB1 (0.40) ABCB1RAPGEF4HPGD
SCHEMBL5498232 0.68 RELA (0.66) ABCB1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230280275-A1 PHOTOACTIVATABLE VIBRATIONAL PROBES AND USES THEREOF CALIFORNIA INSTITUTE OF TECHNOLOGY 2023-09-07 US disclosed