SCHEMBL2620549

SCHEMBL2620549

Cc1c(C(C)c2ccc(O)c(N)c2C)ccc(O)c1N

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.39
TRPA1 O75762 1/20 0.39
CHRM1 P11229 1/20 0.39
SLC6A2 P23975 1/20 0.39
ADRA1A P35348 1/20 0.39
HTR2B P41595 1/20 0.39
ALDH1A1 P00352 5/20 0.38
GAA P10253 4/20 0.38
HIF1A Q16665 2/20 0.38
ALOX12 P18054 1/20 0.38
HTT P42858 1/20 0.38
HSD17B10 Q99714 5/20 0.37
ALOX15 P16050 3/20 0.37
PDE10A Q9Y233 1/20 0.37
MAPT P10636 3/20 0.36
KDM4E B2RXH2 3/20 0.34
USP2 O75604 2/20 0.34
HPGD P15428 2/20 0.34
SCN5A Q14524 1/20 0.34
TDP1 Q9NUW8 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28647277 0.82 TSHR (0.50) LMNATRPA1CHRM1SLC6A2ADRA1A
SCHEMBL4815999 0.78 ALDH1A1 (0.44) TRPA1ALDH1A1GAAHIF1AALOX12
SCHEMBL5190967 0.74 LMNA (0.36) LMNATRPA1CHRM1SLC6A2ADRA1A
SCHEMBL1568810 0.73 ALDH1A1 (0.52) TRPA1ALDH1A1GAAHIF1AALOX12
SCHEMBL118836 0.73 TSHR (0.46) TRPA1ALDH1A1GAAHIF1AALOX12
SCHEMBL16429287 0.73 POLB (0.56) LMNATRPA1ALDH1A1GAAHIF1A
Water SCHEMBL16429286 0.71 POLB (0.54) LMNATRPA1ALDH1A1GAAHIF1A
SCHEMBL9380980 0.71 ALDH1A1 (0.39) TRPA1ALDH1A1GAAALOX12HSD17B10
SCHEMBL7771678 0.71 LMNA (0.42) LMNATRPA1CHRM1SLC6A2ADRA1A
SCHEMBL10934865 0.70 ALDH1A1 (0.38) LMNATRPA1ALDH1A1GAAHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8530119-B2 Positive photosensitive resin composition, cured film, protective film, interlayer insulating film, and semiconductor device and display element using the same SUMITOMO BAKELITE CO., LTD. (JP) 2013-09-10 US disclosed
US-8530119-B2 Positive photosensitive resin composition, cured film, protective film, interlayer insulating film, and semiconductor device and display element using the same SUMITOMO BAKELITE CO., LTD. (JP) 2013-09-10 US disclosed
US-20120100484-A1 POSITIVE PHOTOSENSITIVE RESIN COMPOSITION, CURED FILM, PROTECTIVE FILM, INTERLAYER INSULATING FILM, AND SEMICONDUCTOR DEVICE AND DISPLAY ELEMENT USING THE SAME SUMITOMO BAKELITE CO., LTD. (JP) 2012-04-26 US disclosed
US-20120100484-A1 POSITIVE PHOTOSENSITIVE RESIN COMPOSITION, CURED FILM, PROTECTIVE FILM, INTERLAYER INSULATING FILM, AND SEMICONDUCTOR DEVICE AND DISPLAY ELEMENT USING THE SAME SUMITOMO BAKELITE CO., LTD. (JP) 2012-04-26 US disclosed