SCHEMBL5190967

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3989159	0.81	POLB (0.38)	SCN5AALDH1A1MAPTTSHRPOLB
	SCHEMBL9862044	0.77	TRPA1 (0.38)	LMNAADRA1ATRPA1HTR2BCHRM1
	SCHEMBL4815999	0.74	ALDH1A1 (0.44)	TRPA1SCN5AALDH1A1HIF1AGAA
	SCHEMBL2620549	0.74	LMNA (0.39)	LMNAADRA1ATRPA1HTR2BCHRM1
	SCHEMBL9791485	0.74	POLB (0.39)	LMNAADRA1ATRPA1HTR2BCHRM1
	SCHEMBL10624727	0.72	GABRA1 (0.46)	LMNAADRA1ATRPA1HTR2BSLC6A2
	SCHEMBL1233639	0.70	POLB (0.56)	TRPA1SCN5AALDH1A1GAAHSD17B10
	SCHEMBL30962921	0.70	POLB (0.56)	TRPA1SCN5AALDH1A1GAAHSD17B10
	SCHEMBL4603633	0.70	ALOX15 (0.46)	TRPA1ALDH1A1HIF1AGAAALOX12
	SCHEMBL19998489	0.70	LMNA (0.38)	LMNAADRA1ATRPA1HTR2BCHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.