Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14784289 | 0.83 | ALDH1A1 (0.38) | ALDH1A1HSD17B10ALOX15PDE10AGAA | |
| SCHEMBL26927471 | 0.81 | POLB (0.36) | ALDH1A1TSHRDAOPOLB | |
| SCHEMBL4815999 | 0.81 | ALDH1A1 (0.44) | ALDH1A1HSD17B10ALOX15PDE10AGAA | |
| SCHEMBL30673309 | 0.81 | POLB (0.36) | ALDH1A1TSHRDAOPOLB | |
| SCHEMBL19944381 | 0.79 | TRPA1 (0.40) | ALDH1A1HSD17B10GAACA3CA6 | |
| SCHEMBL29449508 | 0.79 | TRPA1 (0.40) | ALDH1A1HSD17B10GAACA3CA6 | |
| SCHEMBL118836 | 0.77 | TSHR (0.46) | ALDH1A1HSD17B10ALOX15PDE10AGAA | |
| SCHEMBL5511605 | 0.77 | CA3 (0.39) | ALDH1A1HSD17B10ALOX15PDE10AGAA | |
| SCHEMBL22133743 | 0.77 | CA6 (0.39) | ALDH1A1HSD17B10ALOX15CA3CA6 | |
| SCHEMBL1568810 | 0.77 | ALDH1A1 (0.52) | ALDH1A1HSD17B10ALOX15PDE10AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409484-B1 | 4,5,6,7-Tetrasubstituted benzoxazolones | PFIZER (US) | 1994-06-08 | — | — | EP | disclosed |
| US-5071863-A | Antiallergens; antiinflammatory agents; enzyme inhibitors | PFIZER INC. (US) | 1991-12-10 | — | — | US | disclosed |
| EP-0409484-A2 | 4,5,6,7-Tetrasubstituted benzoxazolones | PFIZER INC. (US) | 1991-01-23 | — | — | EP | disclosed |