Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 2/20 | 0.38 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24430074 | 0.91 | MEN1 (0.50) | MEN1KMT2AL3MBTL1GAAG6PD | |
| SCHEMBL24430029 | 0.89 | MEN1 (0.54) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL24437423 | 0.86 | MEN1 (0.50) | MEN1KMT2AL3MBTL1GAAALDH1A1 | |
| SCHEMBL24430115 | 0.82 | MEN1 (0.44) | MEN1KMT2AALDH1A1KDM4ERPS6KA3 | |
| SCHEMBL24430113 | 0.81 | MEN1 (0.54) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL24437348 | 0.81 | MEN1 (0.43) | MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL24430075 | 0.81 | KMT2A (0.45) | MEN1KMT2AL3MBTL1GAAG6PD | |
| SCHEMBL24430080 | 0.80 | MAPT (0.37) | MEN1KMT2AL3MBTL1GAAG6PD | |
| SCHEMBL26205855 | 0.80 | MEN1 (0.52) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL24430026 | 0.80 | KMT2A (0.52) | MEN1KMT2AALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11753374-B2 | Compounds for the treatment of acute and chronic kidney disease | Southern Reserach Institute (US) | 2023-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11753374-B2 | Compounds for the treatment of acute and chronic kidney disease | HMOX1, GLS, HMOX2 | MEN1 4171/4885KMT2A 2088/4885L3MBTL1 1613/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.