SCHEMBL26209641

SCHEMBL26209641

CC1(C)OB(c2cnc(O)c(C#N)c2)OC1(C)C

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GSK3A P49840 1/20 0.36
GSK3B P49841 1/20 0.36
PDGFRB P09619 3/20 0.36
KDR P35968 3/20 0.36
FFAR1 O14842 1/20 0.35
ESR2 Q92731 1/20 0.34
DGAT1 O75907 2/20 0.34
AAK1 Q2M2I8 1/20 0.33
LPL P06858 4/20 0.33
LIPG Q9Y5X9 4/20 0.33
ALPL P05186 1/20 0.31
F11 P03951 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17381643 0.83 CHRNB2 (0.36) GSK3AGSK3BPDGFRBKDRFFAR1
SCHEMBL2120457 0.82 PDGFRB (0.43) GSK3AGSK3BPDGFRBKDRFFAR1
SCHEMBL29857652 0.82 PDGFRB (0.43) GSK3AGSK3BPDGFRBKDRFFAR1
SCHEMBL12327199 0.82 ALDH1A1 (0.42) GSK3AGSK3BPDGFRBKDRFFAR1
SCHEMBL30713566 0.82 LPL (0.38) GSK3AGSK3BPDGFRBKDRFFAR1
SCHEMBL3451096 0.79 ALPL (0.43) GSK3AGSK3BPDGFRBKDRFFAR1
SCHEMBL19212379 0.79 GSK3A (0.33) GSK3AGSK3BPDGFRBKDRFFAR1
SCHEMBL30905953 0.79 ALPL (0.43) GSK3AGSK3BPDGFRBKDRFFAR1
SCHEMBL22685874 0.78 GSK3A (0.39) GSK3AGSK3BPDGFRBKDRFFAR1
SCHEMBL18895034 0.78 LPL (0.42) GSK3AGSK3BPDGFRBKDRFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023146512-A1 COMPOUNDS AND METHODS OF USE THEREOF VIVACE THERAPEUTICS, INC. (US) 2023-08-03 WO disclosed