SCHEMBL262146

SCHEMBL262146

c1ccc(N(c2ccccc2)c2ccc(-c3ccc4[nH]c5ccc(-c6ccc(N(c7ccccc7)c7ccccc7)cc6)cc5c4c3)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK4 P11802 2/20 0.45
CCND1 P24385 2/20 0.45
JAK2 O60674 1/20 0.42
ALDH1A1 P00352 4/20 0.41
KDM4E B2RXH2 2/20 0.41
MAPT P10636 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
AHR P35869 1/20 0.41
GABRA1 P14867 2/20 0.40
GABRG2 P18507 2/20 0.40
GABRB3 P28472 2/20 0.40
GABRA5 P31644 2/20 0.40
GABRA3 P34903 2/20 0.40
GABRA2 P47869 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL263406 0.98 CDK4 (0.48) CDK4CCND1JAK2ALDH1A1KDM4E
SCHEMBL263083 0.98 CDK4 (0.48) CDK4CCND1JAK2ALDH1A1KDM4E
SCHEMBL262852 0.98 CDK4 (0.48) CDK4CCND1JAK2ALDH1A1KDM4E
SCHEMBL18388639 0.96 CDK4 (0.43) CDK4CCND1JAK2ALDH1A1KDM4E
SCHEMBL24531292 0.95 CDK4 (0.46) CDK4CCND1JAK2ALDH1A1KDM4E
SCHEMBL31663617 0.95 AHR (0.50) CDK4CCND1JAK2ALDH1A1KDM4E
SCHEMBL262335 0.95 CDK4 (0.46) CDK4CCND1JAK2ALDH1A1KDM4E
SCHEMBL15685609 0.95 AHR (0.50) CDK4CCND1JAK2ALDH1A1KDM4E
SCHEMBL263271 0.95 AHR (0.50) CDK4CCND1JAK2ALDH1A1KDM4E
SCHEMBL263419 0.95 CDK4 (0.46) CDK4CCND1JAK2ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230159457-A1 FLUORENE DERIVATIVES, POLYMERS OBTAINED FROM SAID FLUORENE DERIVATIVES AND METHOD FOR PREPARING THE SAME IRPC PUBLIC COMPANY LIMITED (TH) 2023-05-25 US disclosed
US-20230159457-A1 FLUORENE DERIVATIVES, POLYMERS OBTAINED FROM SAID FLUORENE DERIVATIVES AND METHOD FOR PREPARING THE SAME IRPC PUBLIC COMPANY LIMITED (TH) 2023-05-25 US disclosed
WO-2021211066-A1 FLUORENE DERIVATIVES, POLYMERS OBTAINED FROM SAID FLUORENE DERIVATIVES AND METHOD FOR PREPARING THE SAME IRPC PUBLIC COMPANY LIMITED (TH) 2021-10-21 WO disclosed
US-20200321533-A1 COMPOUNDS FOR ORGANIC LIGHT EMITTING DIODE MATERIALS THE SCRIPPS RESEARCH INSTITUTE 2020-10-08 US disclosed
US-20180212158-A1 ORGANIC LIGHT-EMITTING DIODE MATERIALS PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2018-07-26 US disclosed
US-20170244049-A1 ORGANIC LIGHT-EMITTING DIODE MATERIALS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2017-08-24 US disclosed
CN-103450700-B A kind of tree-shaped organic dye based on carbazole or triphenylamine derivative and preparing the application in dye sensitization solar battery SUN YAT-SEN UNIVERSITY (CN) 2015-12-02 CN disclosed
US-9136479-B2 Organic compound, anthracene derivative, and light-emitting element, light-emitting device, and electronic device using the anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-09-15 US disclosed
US-9136479-B2 Organic compound, anthracene derivative, and light-emitting element, light-emitting device, and electronic device using the anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-09-15 US disclosed
US-20150004731-A1 ORGANIC COMPOUND, ANTHRACENE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE USING THE ANTHRACENE DERIVATIVE SEMICONDUCTOR ENERGY LAB (JP) 2015-01-01 US disclosed
US-20100200847-A1 ORGANIC COMPOUND, ANTHRACENE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE USING ANTHRACENE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-08-12 US disclosed
US-7723722-B2 Organic compound, anthracene derivative, and light-emitting element, light-emitting device, and electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-05-25 US disclosed
US-7723722-B2 Organic compound, anthracene derivative, and light-emitting element, light-emitting device, and electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-05-25 US disclosed
US-7723722-B2 Organic compound, anthracene derivative, and light-emitting element, light-emitting device, and electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-05-25 US disclosed
WO-2010046259-A1 POLYCYCLIC COMPOUNDS FOR ELECTRONIC APPLICATIONS BASF SE (DE) 2010-04-29 WO disclosed
US-20080242871-A1 N-(9-Aryl-10-anthracenylarylene)carbazole derivatives that are substituted with aditional aromatic amine groups including additional carbzaole rings; light-emitting element that emits blue light at high luminous efficiency and is capable of operation for a long time. SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-10-02 US disclosed
US-20080242871-A1 N-(9-Aryl-10-anthracenylarylene)carbazole derivatives that are substituted with aditional aromatic amine groups including additional carbzaole rings; light-emitting element that emits blue light at high luminous efficiency and is capable of operation for a long time. SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-10-02 US disclosed
US-20080242871-A1 N-(9-Aryl-10-anthracenylarylene)carbazole derivatives that are substituted with aditional aromatic amine groups including additional carbzaole rings; light-emitting element that emits blue light at high luminous efficiency and is capable of operation for a long time. SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-10-02 US disclosed
EP-1972619-A1 Organic compound, anthracene derivative, and light-emitting element, light-emitting device, and electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-09-24 EP disclosed
EP-1972619-A1 Organic compound, anthracene derivative, and light-emitting element, light-emitting device, and electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-09-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200321533-A1 COMPOUNDS FOR ORGANIC LIGHT EMITTING DIODE MATERIALS ALDH1A2, DDT, CLTB CDK4 67/4885CCND1 101/4885JAK2 3749/4885
US-20180212158-A1 ORGANIC LIGHT-EMITTING DIODE MATERIALS MSN, DDT, NECTIN4 CDK4 246/4885CCND1 226/4885JAK2 1697/4885
US-20170244049-A1 ORGANIC LIGHT-EMITTING DIODE MATERIALS CYBA, DDT, DRD1 CDK4 180/4885CCND1 135/4885JAK2 2485/4885
US-20230159457-A1 FLUORENE DERIVATIVES, POLYMERS OBTAINED FROM SAID FLUORENE DERIVATIVES AND METHOD FOR PREPARING THE SAME TERT, F12, F3 CDK4 495/4885CCND1 120/4885JAK2 112/4885
US-20080242871-A1 N-(9-Aryl-10-anthracenylarylene)carbazole derivatives that are substituted with aditional aromatic amine groups including additional carbzaole rings; light-emitting element that emits blue light at high luminous efficiency and is capable of operation for a long time. CYP1A1, AADAT, AADAC CDK4 705/4885CCND1 139/4885JAK2 3224/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.