Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | EED | O75530 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14402586 | 0.72 | TAAR1 (0.41) | SLC6A4CYP3A4CYP2D6SLC6A2SLC6A3 | |
| SCHEMBL26304397 | 0.72 | HRH1 (0.35) | CYP2D6KCNH2MAPT | |
| SCHEMBL25482991 | 0.70 | TAAR1 (0.42) | SLC6A4CYP3A4CYP2D6SLC6A2SLC6A3 | |
| SCHEMBL13849907 | 0.67 | TAS1R3 (0.40) | SLC6A4CYP3A4CYP2D6SLC6A2SLC6A3 | |
| SCHEMBL23352304 | 0.67 | TAAR1 (0.39) | SLC6A4CYP3A4CYP2D6SLC6A2SLC6A3 | |
| SCHEMBL14402510 | 0.67 | TAS1R3 (0.40) | SLC6A4CYP3A4CYP2D6SLC6A2SLC6A3 | |
| SCHEMBL22984964 | 0.67 | TSHR (0.38) | SLC6A4CYP3A4CYP2D6SLC6A2SLC6A3 | |
| SCHEMBL19003563 | 0.67 | HTT (0.42) | MEN1KMT2AMAP4K4HTT | |
| SCHEMBL139640 | 0.66 | GABRA1 (0.52) | SLC6A4CYP3A4CYP2D6SLC6A2SLC6A3 | |
| SCHEMBL23717412 | 0.65 | ADRB1 (0.50) | TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4242202-A1 | BENZIMIDAZOLE DERIVATIVE AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | Shenzhen Salubris Pharmaceuticals Co., Ltd. (CN) | 2023-09-13 | — | — | EP | disclosed |