Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18733781 | 0.83 | DRD2 (0.38) | CHRNB4CHRNA3CHRNB2CHRNA4SIGMAR1 | |
| SCHEMBL17957942 | 0.77 | RARA (0.41) | LTA4H | |
| SCHEMBL17957943 | 0.77 | RARA (0.41) | LTA4H | |
| SCHEMBL17991535 | 0.76 | ALOX15 (0.40) | GAA | |
| SCHEMBL17957744 | 0.75 | HDAC6 (0.44) | — | |
| SCHEMBL17957746 | 0.75 | HDAC6 (0.44) | — | |
| SCHEMBL17958061 | 0.75 | HDAC6 (0.44) | — | |
| SCHEMBL15222074 | 0.74 | SMN1; SMN2 (0.41) | CHRNB4CHRNA3CHRNB2CHRNA4SIGMAR1 | |
| SCHEMBL13091467 | 0.68 | SIGMAR1 (0.36) | SIGMAR1POLB | |
| SCHEMBL25082430 | 0.67 | SIGMAR1 (0.47) | P2RX7LTA4HSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023168298-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | DENALI THERAPEUTICS INC. (US) | 2023-09-07 | — | — | WO | disclosed |