SCHEMBL262389

SCHEMBL262389

Cc1ccccc1N(c1ccccc1)c1ccc(-c2ccc3[nH]c4ccc(-c5ccc(N(c6ccccc6)c6ccccc6C)cc5)cc4c3c2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TNKS2 Q9H2K2 1/20 0.39
CDK4 P11802 1/20 0.38
CCND1 P24385 1/20 0.38
BCHE P06276 1/20 0.37
GABRA1 P14867 2/20 0.37
GABRG2 P18507 2/20 0.37
GABRB3 P28472 2/20 0.37
GABRA5 P31644 2/20 0.37
GABRA3 P34903 2/20 0.37
GABRA2 P47869 2/20 0.37
GABRA6 Q16445 2/20 0.37
HTR7 P34969 1/20 0.36
HTR6 P50406 1/20 0.36
KIF11 P52732 1/20 0.35
KMT2A Q03164 4/20 0.35
NPC1 O15118 3/20 0.35
MEN1 O00255 3/20 0.35
JAK2 O60674 1/20 0.35
POLB P06746 1/20 0.35
KDM4E B2RXH2 5/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL263166 0.96 KIF11 (0.42) TNKS2CDK4CCND1KIF11KMT2A
SCHEMBL263218 0.94 TNKS2 (0.38) TNKS2CDK4CCND1BCHEGABRA1
SCHEMBL263394 0.90 KIF11 (0.44) TNKS2KIF11KMT2ANPC1MEN1
SCHEMBL263068 0.85 BCHE (0.48) CDK4CCND1BCHEGABRA1GABRG2
SCHEMBL26058924 0.85 HTR2B (0.39) CDK4CCND1KIF11KMT2ANPC1
SCHEMBL262146 0.85 CDK4 (0.45) TNKS2CDK4CCND1GABRA1GABRG2
SCHEMBL263211 0.84 BCHE (0.43) TNKS2CDK4CCND1BCHEGABRA1
SCHEMBL22182144 0.83 TNKS2 (0.37) TNKS2KDM4EMAPTALDH1A1
SCHEMBL263406 0.83 CDK4 (0.48) TNKS2CDK4CCND1BCHEGABRA1
SCHEMBL263083 0.83 CDK4 (0.48) TNKS2CDK4CCND1BCHEGABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9136479-B2 Organic compound, anthracene derivative, and light-emitting element, light-emitting device, and electronic device using the anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-09-15 US disclosed
US-8816098-B2 Organic compound, anthracene derivative, and light-emitting element, light-emitting device, and electronic device using the anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-08-26 US disclosed
US-8530672-B2 Organic compound, anthracene derivative, and light-emitting element, light-emitting device, and electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-09-10 US disclosed
US-20120309984-A1 ORGANIC COMPOUND, ANTHRACENE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE USING ANTHRACENE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-12-06 US disclosed
US-8278655-B2 Organic compound, anthracene derivative, and light-emitting element, light-emitting device, and electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-10-02 US disclosed
US-20120104379-A1 ORGANIC COMPOUND, ANTHRACENE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE USING ANTHRACENE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-05-03 US disclosed
US-8134147-B2 Organic compound, anthracene derivative, and light-emitting element, light-emitting device, and electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-03-13 US disclosed
US-8134147-B2 Organic compound, anthracene derivative, and light-emitting element, light-emitting device, and electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-03-13 US disclosed
US-20100200847-A1 ORGANIC COMPOUND, ANTHRACENE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE USING ANTHRACENE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-08-12 US disclosed
US-20100200847-A1 ORGANIC COMPOUND, ANTHRACENE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE USING ANTHRACENE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-08-12 US disclosed
US-7723722-B2 Organic compound, anthracene derivative, and light-emitting element, light-emitting device, and electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-05-25 US disclosed
US-7723722-B2 Organic compound, anthracene derivative, and light-emitting element, light-emitting device, and electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-05-25 US disclosed
US-20080242871-A1 N-(9-Aryl-10-anthracenylarylene)carbazole derivatives that are substituted with aditional aromatic amine groups including additional carbzaole rings; light-emitting element that emits blue light at high luminous efficiency and is capable of operation for a long time. SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-10-02 US disclosed
US-20080242871-A1 N-(9-Aryl-10-anthracenylarylene)carbazole derivatives that are substituted with aditional aromatic amine groups including additional carbzaole rings; light-emitting element that emits blue light at high luminous efficiency and is capable of operation for a long time. SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-10-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120104379-A1 ORGANIC COMPOUND, ANTHRACENE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE USING ANTHRACENE DERIVATIVE CYP1A1, XPO7, AMY1A TNKS2 2946/4885CDK4 1732/4885CCND1 141/4885
US-20120309984-A1 ORGANIC COMPOUND, ANTHRACENE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE USING ANTHRACENE DERIVATIVE CYP1A1, XPO7, AMY1A TNKS2 2946/4885CDK4 1732/4885CCND1 141/4885
US-20080242871-A1 N-(9-Aryl-10-anthracenylarylene)carbazole derivatives that are substituted with aditional aromatic amine groups including additional carbzaole rings; light-emitting element that emits blue light at high luminous efficiency and is capable of operation for a long time. CYP1A1, AADAT, AADAC TNKS2 3195/4885CDK4 705/4885CCND1 139/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.