Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | CCR4 | P51679 | 1/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2185845 | 1.00 | FFAR2 (0.51) | FFAR2GAANPC1ALDH1A1MAPT | |
| SCHEMBL1820481 | 1.00 | FFAR2 (0.51) | FFAR2GAANPC1ALDH1A1MAPT | |
| SCHEMBL2185593 | 0.99 | FFAR2 (0.50) | FFAR2GAANPC1ALDH1A1MAPT | |
| SCHEMBL27818106 | 0.99 | FFAR2 (0.50) | FFAR2GAANPC1ALDH1A1MAPT | |
| SCHEMBL262345 | 0.91 | FFAR2 (0.47) | FFAR2GAANPC1ALDH1A1MAPT | |
| SCHEMBL2303876 | 0.90 | FFAR2 (0.51) | FFAR2GAANPC1ALDH1A1MAPT | |
| SCHEMBL2303870 | 0.90 | FFAR2 (0.51) | FFAR2GAANPC1ALDH1A1MAPT | |
| SCHEMBL262169 | 0.90 | FFAR2 (0.51) | FFAR2GAANPC1ALDH1A1MAPT | |
| SCHEMBL15402199 | 0.90 | FFAR2 (0.49) | FFAR2GAANPC1ALDH1A1MAPT | |
| SCHEMBL2183898 | 0.90 | FFAR2 (0.49) | FFAR2GAANPC1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346841-B1 | 2-ARYL-PROPIONIC ACIDS AND DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DOMPÉ S P A (IT) | 2015-01-14 | — | — | EP | claimed |
| US-20260076949-A1 | STABLE MONOHYDRATE OF DF2755A AND PROCESS FOR ITS PREPARATION | DOMPE FARM SPA (IT) | 2026-03-19 | — | — | US | disclosed |
| EP-4655290-A1 | STABLE MONOHYDRATE OF DF2755A AND PROCESS FOR ITS PREPARATION | Dompé farmaceutici S.p.A. (IT) | 2025-12-03 | — | — | EP | disclosed |
| WO-2024156857-A1 | STABLE MONOHYDRATE OF DF2755A AND PROCESS FOR ITS PREPARATION | DOMPE' FARMACEUTICI SPA (IT) | 2024-08-02 | — | — | WO | disclosed |
| EP-4406942-A1 | STABLE MONOHYDRATE OF DF2755A AND PROCESS FOR ITS PREPARATION | Dompe' Farmaceutici S.P.A. (IT) | 2024-07-31 | — | — | EP | disclosed |
| EP-2346841-B1 | 2-ARYL-PROPIONIC ACIDS AND DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DOMPÉ S P A (IT) | 2015-01-14 | — | — | EP | disclosed |
| CN-101827841-B | (R)-4-(heteroaryl) phenylethyl derivatives and pharmaceutical compositions containing them | DOMPE SPA | 2012-11-28 | — | — | CN | disclosed |
| US-8133911-B2 | (R)-4-(heteroaryl) phenylethyl derivatives and pharmaceutical compositions containing them | DOMPE S.P.A (IT) | 2012-03-13 | — | — | US | disclosed |
| EP-2201006-B1 | (R)-4-(HETEROARYL) PHENYLETHYL DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DOMPE SPA (IT) | 2011-03-09 | — | — | EP | disclosed |
| US-20100249198-A1 | (R)-4-(HETEROARYL) PHENYLETHYL DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DOMPE S.P.A (IT) | 2010-09-30 | — | — | US | disclosed |
| CN-101827841-A | (R)-4-(heteroaryl) styroyl derivative and pharmaceutical composition thereof | DOMPE SPA | 2010-09-08 | — | — | CN | disclosed |
| EP-2201006-A1 | (R)-4-(HETEROARYL) PHENYLETHYL DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Dompé S.p.a. (IT) | 2010-06-30 | — | — | EP | disclosed |
| WO-2009050258-A1 | (R)-4-(HETEROARYL) PHENYLETHYL DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Dompé S.p.A. (IT) | 2009-04-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249198-A1 | (R)-4-(HETEROARYL) PHENYLETHYL DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | C3AR1, C5AR2, C5AR1 | FFAR2 631/4885GAA 4381/4885NPC1 2924/4885 |
| US-20260076949-A1 | STABLE MONOHYDRATE OF DF2755A AND PROCESS FOR ITS PREPARATION | SLC30A5, PDHA1, PDHA2 | FFAR2 305/4885GAA 580/4885NPC1 567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.