SCHEMBL26246781

SCHEMBL26246781

CSCC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(C)cc1)NC(=O)[C@H](CCc1ccccc1)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CCCCN)C(C)C)C(C)C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
IL23R Q5VWK5 9/20 0.54
GLP1R P43220 1/20 0.54
GCGR P47871 1/20 0.54
GIPR P48546 1/20 0.54
PTH1R Q03431 3/20 0.53
CD47 Q08722 1/20 0.51
C5AR1 P21730 1/20 0.51
GHSR Q92847 3/20 0.50
NPY2R P49146 1/20 0.50
RXFP1 Q9HBX9 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16692892 0.93 IL23R (0.61) IL23RGLP1RGCGRGIPRCD47
SCHEMBL16692898 0.93 IL23R (0.61) IL23RGLP1RGCGRGIPRCD47
SCHEMBL19731206 0.93 IL23R (0.61) IL23RGLP1RGCGRGIPRCD47
SCHEMBL16692899 0.93 IL23R (0.61) IL23RGLP1RGCGRGIPRCD47
SCHEMBL19731216 0.93 IL23R (0.61) IL23RGLP1RGCGRGIPRCD47
SCHEMBL24172454 0.93 IL23R (0.61) IL23RGLP1RGCGRGIPRCD47
SCHEMBL19731215 0.93 GLP1R (0.61) IL23RGLP1RGCGRGIPRCD47
SCHEMBL29973095 0.91 GHSR (0.57) IL23RGLP1RGCGRGIPRGHSR
SCHEMBL21185972 0.90 IL23R (0.65) IL23R
SCHEMBL30130542 0.88 IL23R (0.55) IL23RCD47C5AR1GHSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11759496-B2 Compounds and pharmaceutical use thereof in the treatment of cancer Karoyan, Philippe (FR) 2023-09-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11759496-B2 Compounds and pharmaceutical use thereof in the treatment of cancer VIP, RNASE1, ABCB11 IL23R 581/4885GLP1R 1060/4885GCGR 1973/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.