Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | ACACA | Q13085 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | L3MBTL3 | Q96JM7 | 5/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.34 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.34 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.34 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19652192 | 0.87 | ADRA1A (0.47) | ALDH1A1ADRA1A | |
| SCHEMBL19652190 | 0.86 | KDM4E (0.48) | KDM4EKMT2AALDH1A1ACACBACACA | |
| SCHEMBL26254614 | 0.84 | L3MBTL3 (0.39) | KDM4ESMN1; SMN2KMT2AALDH1A1ACACB | |
| SCHEMBL26138927 | 0.83 | KMT2A (0.36) | KDM4ESMN1; SMN2KMT2AALDH1A1ACACB | |
| SCHEMBL12156267 | 0.81 | L3MBTL3 (0.51) | KMT2AL3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL26252044 | 0.81 | MGLL (0.38) | KDM4EKMT2AALDH1A1ADRA1ANPC1 | |
| SCHEMBL762451 | 0.81 | ALDH1A1 (0.50) | SMN1; SMN2KMT2AALDH1A1TP53NPC1 | |
| SCHEMBL12156517 | 0.80 | L3MBTL3 (0.53) | KDM4EKMT2AALDH1A1L3MBTL3L3MBTL1 | |
| SCHEMBL21561083 | 0.79 | KDM4E (0.42) | KDM4ESMN1; SMN2KMT2AALDH1A1TDP1 | |
| SCHEMBL18269488 | 0.79 | L3MBTL3 (0.48) | ALDH1A1ACACBACACAL3MBTL3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230265103-A1 | NOVEL INHIBITORS OF PIKFYVE AND METHODS USING SAME | TME THERAPEUTICS LLC | 2023-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230265103-A1 | NOVEL INHIBITORS OF PIKFYVE AND METHODS USING SAME | PIKFYVE, PIK3CD, PIK3R5 | KDM4E 1554/4885SMN1; SMN2 3149/4885KMT2A 3662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.